Tag: Vaccines and Immunization
Groundbreaking study shows potential of new mRNA vaccine to help fight tuberculosis
A new vaccine that boosts immunity against tuberculosis (TB) has been shown to be effective in pioneering pre-clinical trials.
Cell-based glycoengineering for production of homogeneous and specific glycoform-enriched antibodies with improved effector functions
Towards more efficient synthetic immunomodulators: biological characterization and mechanism of action of monosaccharide-derived TLR4 agonists
Toll-like receptors (TLRs), including TLR4, play a crucial role in innate immunity activation, and small molecular TLR4 activators (agonists) are in preclinical and clinical phase of development as vaccine adjuvant or tumor immunotherapeuutics. .Recently, we have generated novel glucosamine-derived compounds, FP molecules, that are active as TLR4 agonists. Despite their chemical structure different from LPS,… Continue reading Towards more efficient synthetic immunomodulators: biological characterization and mechanism of action of monosaccharide-derived TLR4 agonists
[ASAP] Oral DNA Vaccine Utilizing the Yeast Cell Wall for Dectin-1 Receptor-Mediated Enhancement of Mucosal Immunity
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.4c00943
TWiV 1193: HPV or not to B
TWiV reviews a facility accident that killed monkeys, new bird blu genotype found in Nevada dairy cattle, Argentina plans to leave WHO, yellow fever on the rise, dynamics of HPV infections in women, and Epstein-Barr virus protein targets B cell receptor for degradation. Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli Click arrow to playDownload TWiV… Continue reading TWiV 1193: HPV or not to B
TWiV 1192: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss confirmation of Robert F Kennedy as HHS sectary, mpox, Ebola, how the American people support vaccine development and administration, the measles outbreak in the US-Texas, Georgia and influenza: the number of human infections, high avian flu in mammals, house cats and dairy cows before… Continue reading TWiV 1192: Clinical update with Dr. Daniel Griffin
Small RNA and Toll-like receptor interactions: origins and disease mechanisms
Linking vaccine adjuvant mechanisms of action to function
Science Immunology, Volume 10, Issue 104, February 2025.
Immunocompromised individuals need regular boosters for Covid-19 protection
Vaccinations alone may not be enough to protect people with compromised immune systems from infection, even if the vaccine has generated the production of antibodies, new research from the University of Cambridge has shown. The findings, published today in Science Advances, suggest that such individuals will need regular vaccine boosters to protect them and reduce… Continue reading Immunocompromised individuals need regular boosters for Covid-19 protection