[In Context] Angela Dos Santos

AI SummaryAngela Dos Santos is Australia’s first Aboriginal neurologist, trained in neurology and stroke medicine at various prestigious hospitals. She currently works as a neurologist and stroke physician at multiple institutions and holds positions as a Scientia Fellow at the University of New South Wales and a Senior Clinical Research Fellow for the Australian Stroke… Continue reading [In Context] Angela Dos Santos

[In Context] Globally advancing neurological education in headache

AI SummaryThis article discusses the importance of advancing neurological education in headache disorders, as nearly 16% of the world’s population experience headaches daily. Recognizing different types of headaches and addressing their effects is crucial for promoting brain health, a priority outlined by the WHO in its Intersectoral Global Action Plan on Epilepsy and Other Neurological… Continue reading [In Context] Globally advancing neurological education in headache

[ASAP] Anaerobic Glycolysis and Ischemic Stroke: From Mechanisms and Signaling Pathways to Natural Product Therapy

AI SummaryThis article explores the role of anaerobic glycolysis in ischemic stroke, including the mechanisms and signaling pathways involved. It also discusses the potential of natural product therapy in the treatment of this condition. The focus is on understanding the metabolic changes that occur during ischemic stroke and how these can be targeted for therapeutic… Continue reading [ASAP] Anaerobic Glycolysis and Ischemic Stroke: From Mechanisms and Signaling Pathways to Natural Product Therapy

ED Visits for Falls Linked to Higher Short-Term Stroke Risk

AI SummarySummary: A study found that older patients, women, and those with vascular comorbidities have a higher short-term risk of stroke after visiting the emergency department for a fall.Older patients, women, and those with vascular comorbidities had an increased risk for stroke after an ED treat-and release visit for a fall, found a study. Medscape… Continue reading ED Visits for Falls Linked to Higher Short-Term Stroke Risk

Derivation and Validation of ICD-10 Codes for Identifying Incident Stroke

AI SummaryThis study focuses on creating and validating ICD-10 codes that can accurately identify incident stroke cases in Medicare inpatient fee-for-service claims data. The research addresses the need for reliable coding systems to track and analyze stroke events, which can have significant implications for improving stroke detection, treatment, and outcomes.This cohort study assesses the derivation… Continue reading Derivation and Validation of ICD-10 Codes for Identifying Incident Stroke

Errors in Table 1 and Figure 2

AI SummaryThis content provides corrections made to errors found in Table 1 and Figure 2 of an Original Investigation regarding the effects of Tirofiban on neurological deterioration in patients with acute ischemic stroke. The corrected values include the location of cerebral infarction and the unit of measure for time from onset to randomization.In the Original… Continue reading Errors in Table 1 and Figure 2

Recurrent Ischemic Stroke in Patients With Atrial Fibrillation While Receiving Oral Anticoagulants

AI SummaryThis cohort study in Denmark examines the association between discontinuation of oral anticoagulation and the risk of recurrent ischemic stroke in patients with atrial fibrillation. The study aims to provide insights into the impact of anticoagulant therapy on stroke prevention in this patient population.This cohort study of patients in Denmark with atrial fibrillation investigates… Continue reading Recurrent Ischemic Stroke in Patients With Atrial Fibrillation While Receiving Oral Anticoagulants

New in Neurology: Colchicine, GLP-1s, and Motor Disorders

AI SummaryThis article discusses recent updates in neurology related to stroke care, sleep apnea, antipsychotics and dementia, as well as treatments for motor disorders. Key topics include the use of colchicine, GLP-1s, and other therapies in neurological conditions. Prof Christoph Diener provides insights into these advancements in the field of neurology.Prof Christoph Diener discusses recent… Continue reading New in Neurology: Colchicine, GLP-1s, and Motor Disorders

Brain ischemia causes systemic Notch1 activity in endothelial cells to drive atherosclerosis

Whether stroke induces sustained pro-inflammatory and proatherogenic endothelial alterations in systemic vessels remains poorly understood. Liu et al. find that brain ischemia induces the persistent activation of endothelial Notch1 signaling in the periphery. A sustained increase of circulating Notch1 ligands leads to a senescent, pro-inflammatory endothelium that drives atheroprogression following stroke, which can be therapeutically targeted by blocking antibodies.