In literate adults, an area along the left posterior fusiform gyrus that is often referred to as the “visual word form area” (VWFA) responds particularly strongly to written characters compared with other visually similar stimuli. Theoretical accounts differ in whether they attribute the strong left-lateralization of the VWFA to a left-hemisphere (LH) bias toward visual… Continue reading Right-Lateralization of the Visual Word Form Area after Left-Hemisphere Perinatal Stroke
Tag: Stroke
FDA Okays Tenecteplase for Acute Ischemic Stroke
Tenecteplase is administered as a single, 5-second intravenous bolus, providing a faster and simpler option compared to the standard 60-minute infusion of alteplase. Medscape Medical News
Smoking Linked to Twofold Higher Risk for Ischemic Stroke
Smoking is strongly linked to risk for cryptogenic ischemic stroke in young adults, with the highest risk noted in men and those aged 45-49 years, a study showed. Medscape Medical News
After the Crisis: The Role of Palliative Care in Stroke
A new AHA statement highlights palliative care benefits after stroke, but more research is needed to find the best ways to support this diverse patient group. Medscape Medical News
Hot Topics From the International Stroke Conference
Prof Christoph Diener picks his top trials from the 2025 International Stroke Conference covering thrombectomy for distal stroke, thrombolysis timing, and anticoagulation options in AF. Medscape Neurology
[ASAP] Thiophene Sulfone Single Crystal as a Reversible Thermoelastic Linear Actuator with an Extended Stroke and Second-Harmonic Generation Switching
[ASAP] Optical Spectroscopy of Cerebral Blood Flow for Tissue Interrogation in Ischemic Stroke Diagnosis
Microvascular Dysfunction, Mitochondrial Reprogramming, and Inflammasome Activation as Critical Regulators of Ischemic Stroke Severity Induced by Chronic Exposure to Prescription Opioids
The opioid epidemic endangers not only public health but also social and economic welfare. Growing clinical evidence indicates that chronic use of prescription opioids may contribute to an elevated risk of ischemic stroke and negatively impact poststroke recovery. In addition, NLRP3 inflammasome activation has been related to several cerebrovascular diseases, including ischemic stroke. Interestingly, an… Continue reading Microvascular Dysfunction, Mitochondrial Reprogramming, and Inflammasome Activation as Critical Regulators of Ischemic Stroke Severity Induced by Chronic Exposure to Prescription Opioids
[Articles] Safety and efficacy of nerinetide in patients with acute ischaemic stroke enrolled in the early window: a post-hoc meta-analysis of individual patient data from three randomised trials
Nerinetide showed a clinically significant benefit over several outcome measures, including the modified Rankin Scale score, the incidence of stroke worsening, and infarction volumes. Neuroprotection with nerinetide might, therefore, be indicated for patients within 3 h of stroke onset and who are selected for reperfusion. These inclusion criteria should be tested in a future trial.
[Comment] Neuroprotection in acute ischaemic stroke: reasons for optimism?
The challenges of translating neuroprotective interventions with promising efficacy in animal studies into effective treatments for patients with stroke are well documented, with issues including overoptimistic therapeutic windows, poor bioavailability, and heterogeneous clinical cohorts.1,2 Yet, preservation of the ischaemic penumbra during emergency stroke care remains an attractive concept. In The Lancet Neurology, Michael Tymianski and… Continue reading [Comment] Neuroprotection in acute ischaemic stroke: reasons for optimism?