AI SummaryPesticide exposure is associated with a higher risk of ALS, according to new research. (Summary unavailable)Pesticide exposure is linked to more than a twofold increased risk for ALS, new research that validates a novel environmental risk score suggests. Medscape Medical News
Tag: Sensory and Motor Systems
Early Action Error Processing Is Due to Domain-General Surprise, Whereas Later Processing Is Error Specific
AI SummaryThe ability to adapt behavior after making mistakes is an important aspect of cognitive control. Recent research challenges the idea that slowing down after errors is adaptive, suggesting it may be a result of the surprising nature of errors. This study used EEG decoding to examine whether there are unique error-specific processes that contribute… Continue reading Early Action Error Processing Is Due to Domain-General Surprise, Whereas Later Processing Is Error Specific
Rapid Processing of Observed Touch through Social Perceptual Brain Regions: An EEG-fMRI Fusion Study
Seeing social touch triggers a strong social-affective response that involves multiple brain networks, including visual, social perceptual, and somatosensory systems. Previous studies have identified the specific functional role of each system, but little is known about the speed and directionality of the information flow. Is this information extracted via the social perceptual system or from… Continue reading Rapid Processing of Observed Touch through Social Perceptual Brain Regions: An EEG-fMRI Fusion Study
Tuned to Tremor: Increased Sensitivity of Cortico-Basal Ganglia Neurons to Tremor Frequency in the MPTP Nonhuman Primate Model of Parkinson’s Disease
AI SummaryRest tremor in Parkinson’s disease may be caused by a resonance phenomenon in the brain. The study found that cortico-basal ganglia neurons become more sensitive to tremor frequency in the parkinsonian state. This suggests that these neurons not only switch on tremor but also play a role in setting its frequency.Rest tremor is one… Continue reading Tuned to Tremor: Increased Sensitivity of Cortico-Basal Ganglia Neurons to Tremor Frequency in the MPTP Nonhuman Primate Model of Parkinson’s Disease
Tech to Restore Voice, Expression in ALS and Beyond
Pioneering research using brain computer interfaces can bring speech to the voiceless. Although challenges remain, this neuroscientist sees a day when this technology will be widespread. Medscape Neurology
[ASAP] Shared and Unique Disease Pathways in Amyotrophic Lateral Sclerosis and Parkinson’s Disease Unveiled in Peripheral Blood Mononuclear Cells
Epidemiologic Trends of Amyotrophic Lateral Sclerosis in Ireland, 1996-2021
AI SummaryThe study examined changes in the incidence, prevalence, age at onset, and survival of patients with ALS in Ireland over 25 years. The incidence, prevalence, and age at onset of ALS have all increased, while survival rates have not changed.Background and Objectives The objective of this study was to examine changes to the incidence,… Continue reading Epidemiologic Trends of Amyotrophic Lateral Sclerosis in Ireland, 1996-2021
Recognition of Movement Disorders in Genetic, Developmental, and Epileptic Encephalopathies: More Than Seizures and Neurocognitive Problems
With the roaring discovery of genes responsible for early onset epilepsy, the developmental and epileptic encephalopathies (DEEs) have gained interest for neurologists and epileptologists.1,2
Movement Disorders in Patients With Genetic Developmental and Epileptic Encephalopathies
Background and Objectives Movement disorders (MDs) are underrecognized in the developmental and epileptic encephalopathies (DEEs). There are now more than 800 genes implicated in causing the DEEs; relatively few of these rare genetic diseases are known to be associated with MDs. We identified patients with genetic DEEs who had MDs, classified the nature of their… Continue reading Movement Disorders in Patients With Genetic Developmental and Epileptic Encephalopathies
Treatable Sydenham Chorea in a 76-Year-Old Woman
AI SummaryA 76-year-old woman with asymmetric chorea and no brain lesions has an increased striatal metabolism. She has an elevated anti-streptolysin O titer, indicating a possible Sydenham chorea. Treatment with clarithromycin and immunomodulatory medication improves her movement disorder.A 76-year-old woman presented with asymmetric chorea (Video 1) that has evolved within the past 6 weeks before… Continue reading Treatable Sydenham Chorea in a 76-Year-Old Woman