Cancer, EarlyView.
Tag: Retroviruses
Assessing the impact of HIV status on cervical cancer treatment outcomes in Botswana: A commentary
Cancer, EarlyView.
An antidiabetic helps the immune system recognize reservoirs of HIV
AI SummaryThis article discusses how the antidiabetic drug Metformin could aid in identifying and depleting reservoirs of HIV in individuals with the virus who are undergoing antiretroviral therapy. This could potentially lead to the complete elimination of the viral reservoir.Metformin, a drug used to treat type 2 diabetes, could help deplete the viral reservoir and… Continue reading An antidiabetic helps the immune system recognize reservoirs of HIV
Conformations of membrane human immunodeficiency virus (HIV-1) envelope glycoproteins solubilized in Amphipol A18 lipid-nanodiscs
DNA from Ancient Viruses Helps Many Cancers Grow
AI SummarySummary: A new study has discovered that DNA fragments from ancient retroviruses, particularly LTR10, are active in various cancers and can turn on cancer-related genes.DNAs fragment from retroviruses that are millions of years old appear to be active in a variety of cancers, a new study found. One virus-derived DNA fragment in particular, known… Continue reading DNA from Ancient Viruses Helps Many Cancers Grow
Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env
Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics
Breadth and polyfunctionality of T cell responses to human cytomegalovirus in men who have sex with men: relationship with HIV infection and frailty
Human immunodeficiency virus-associated lymphomas: EHA–ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
AI SummaryThis clinical practice guideline focuses on the diagnosis, treatment, and follow-up of human immunodeficiency virus-associated lymphomas, specifically non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL). Despite a decrease in the incidence of HIV-associated NHL with the introduction of combination antiretroviral therapy (ART), NHL remains a common type of cancer in individuals living with HIV. Incidences… Continue reading Human immunodeficiency virus-associated lymphomas: EHA–ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells
AI SummaryThis article discusses a case study of a male who achieved sustained HIV remission after receiving allogeneic hematopoietic stem cell transplantation from a wild-type CCR5 donor, rather than a CCR5Δ32 homozygous donor. The patient’s plasma viral load remained undetectable for 32 months after stopping antiretroviral treatment. The study suggests that HIV remission may be… Continue reading Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells