Tag: Redox Biochemistry
Copper-detection tool designed to discover possible chelation target for lung cancer
Copper chelation shows promising results in certain lung cancers where cells have two related phenomena: a heightened transcription factor responding to oxidative stress and a diminished level of bioavailable copper. Copper imbalances have long been implicated in cancer cell growth and other disease states.
[ASAP] Ceria Nanoparticles Improve the Quality of Aging Oocytes in Mice by Enhancing ROS Scavenging Ability
ACS Applied Bio MaterialsDOI: 10.1021/acsabm.4c01086
Discovery of a novel pyrimidine derivative for treatment of acute lung injury through reducing oxidative stress and inflammatory response
Acute lung injury (ALI) is a multifactorial respiratory disease characterized by uncontrolled inflammatory response and has high morbidity and mortality. There is currently a lack of effective drug for ALI treatment. In this study, through the nitric oxide (NO) release inhibition and cytotoxicity screening from in-house compound library, hit compound 6 was discovered. Using 2,4,5-trichloropyrimidine… Continue reading Discovery of a novel pyrimidine derivative for treatment of acute lung injury through reducing oxidative stress and inflammatory response
[ASAP] Network-Based Drug Optimization toward the Treatment of Parkinson’s Disease: NRF2, MAO-B, Oxidative Stress, and Chronic Neuroinflammation
Yellow dye from the bloodred webcap fungus may be harmful to humans—red dye could be a safe alternative
[ASAP] Hypoxia-Initiated Supramolecular Free Radicals Induce Intracellular Polymerization for Precision Tumor Therapy
[ASAP] Cathode Design Based on Nitrogen Redox and Linear Coordination of Cu Center for All-Solid-State Fluoride-Ion Batteries
Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis
Ischemic stroke (IS) is a common cerebrovascular disease. Although the formation of atherosclerosis, which is closely related to oxidative stress (OS), is associated with stroke-related deaths. However, the ro…
[ASAP] Macrophage Membrane-Cloaked ROS-Responsive Albumin Nanoplatforms for Targeted Delivery of Curcumin to Alleviate Acute Liver Injury
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.4c00808