Tag: Parkinson’s Disease
Hearing Loss and PD Risk Mitigated by Early Hearing Aid Use
Hearing loss was associated with an increased risk for Parkinson’s disease over 10 years, but early use of hearing aids reduced this risk, a new study shows. Medscape Medical News
Repetitive transcranial magnetic stimulation alleviates motor impairment in Parkinson’s disease: association with peripheral inflammatory regulatory T-cells and SYT6
Repetitive transcranial magnetic stimulation (rTMS) has been used to treat various neurological disorders. However, the molecular mechanism underlying the therapeutic effect of rTMS on Parkinson’s disease (PD)…
Gut-first Parkinson’s disease is encoded by gut dysbiome
In Parkinson’s patients, intestinal dysbiosis can occur years before clinical diagnosis, implicating the gut and its microbiota in the disease. Recent evidence suggests the gut microbiota may trigger body-first P…
Brain pathways that control dopamine release may influence motor control
Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that initiates movement (“go”) and one that suppresses it (“no-go”). In a new study, MIT researchers have discovered an additional two pathways that arise… Continue reading Brain pathways that control dopamine release may influence motor control
Brain pathways that control dopamine release may influence motor control
Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that initiates movement (“go”) and one that suppresses it (“no-go”). In a new study, MIT researchers have discovered an additional two pathways that arise… Continue reading Brain pathways that control dopamine release may influence motor control
Brain pathways that control dopamine release may influence motor control
Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that initiates movement (“go”) and one that suppresses it (“no-go”). In a new study, MIT researchers have discovered an additional two pathways that arise… Continue reading Brain pathways that control dopamine release may influence motor control
Parkinson’s Disease: Care and Comprehensive Treatment
Alberto J. Espay, MD, MSc, comments on the tension between viewing Parkinson’s disease as unique to each patient and the prospect of universal treatments. Medscape
The Misconception of a Biological Definition for Parkinson’s
Dr Espay warns against relying on a new test for Parkinson’s that may blur the line between pathology and actual disease. Medscape
[Comment] The global dimension of Parkinson’s disease genetics
Since 1997, with the discovery of the Parkinson’s disease-causing Ala53Thr variant in SNCA, the gene that encodes α-synuclein,1 our understanding of this common neurodegenerative disease has fundamentally changed, mainly due to a large number of genetic discoveries over the past 25 years. This journey is extensively and elegantly summarised by Shen-Yang Lim and colleagues in… Continue reading [Comment] The global dimension of Parkinson’s disease genetics