In China, Cervical cancer is one of the common malignant tumors in females, and high-risk human papillomavirus (HR-HPV) infection is one of its main causative factors. However, human papillomavirus (HPV) infec… Continue reading on BioMed Central
Tag: Oncogenic Viruses
Immunotherapy’s “Sweet” Future: Wrapping up AACR IO 2025 With Glyco-immunology
The closing keynote session of the inaugural AACR IO painted an exciting picture of the emerging frontier of glyco-immunology, with Jessica Stark, PhD, and Gabriel Rabinovich, PhD, highlighting the profound immunological influence of glycans and the potential power of targeting glyco-immune checkpoints. Earlier on the final day of the conference, held February 23-26 in Los… Continue reading Immunotherapy’s “Sweet” Future: Wrapping up AACR IO 2025 With Glyco-immunology
The HPV Vaccine: Safe, Effective, Prevents Cancer
In the United States, human papillomavirus (HPV) is the most common sexually transmitted infection, according to the US Centers for Disease Control and Prevention (CDC). These infections are so common, it’s thought that almost all men and women will eventually get an infection with some kind of HPV. March 4 is International HPV Awareness Day.… Continue reading The HPV Vaccine: Safe, Effective, Prevents Cancer
The HPV Vaccine: Safe, Effective, Prevents Cancer
In the United States, human papillomavirus (HPV) is the most common sexually transmitted infection, according to the US Centers for Disease Control and Prevention (CDC). These infections are so common, it’s thought that almost all men and women will eventually get an infection with some kind of HPV. March 4 is International HPV Awareness Day.… Continue reading The HPV Vaccine: Safe, Effective, Prevents Cancer
In the activation of HPV-specific human B cells HPV-VLP vaccines mimic membrane-associated antigens
A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers
Direct skin-to-skin contact during intimate sexual contact with a human papillomavirus (HPV)-positive individual is often the cause of HPV infection. In addition, many studies have been written up to date that… Continue reading on BioMed Central
Ubiquitin and ubiquitin-like proteins in HPV-driven carcinogenesis
Abstract Persistent infection with high-risk (HR) human papillomaviruses (HPVs) is responsible for approximately 5% of cancer cases worldwide, including a growing number of oropharyngeal and anogenital cancers. The major HPV oncoproteins, E6 and E7, act together to manipulate cellular pathways involved in the regulation of proliferation, the cell cycle and cell survival, ultimately driving malignant… Continue reading Ubiquitin and ubiquitin-like proteins in HPV-driven carcinogenesis
Activating transcription factor 3 induces oxidative stress and genotoxicity, transcriptionally modulating metastasis-related gene expression in human papillomavirus-infected cervical cancer
Activating Transcription Factor 3 (ATF3) is known for its tumor-suppressive properties in cervical cancer, particularly through its role in stress response and interactions with human papillomavirus (HPV) onco… Continue reading on BioMed Central
Discovery paves way for new hepatitis B treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, research led by Memorial Sloan Kettering Cancer Center (MSK), Weill Cornell Medicine, and The Rockefeller University identified a vulnerability that opens the door to new treatments. The team successfully disrupted the… Continue reading Discovery paves way for new hepatitis B treatment
Editors’ Picks, February 2025: Improving CAR T, Studying Breast Cancer Risk, and More
Cover of Blood Cancer Discovery depicting how CAR T cells using various combinations of chimeric receptors may improve specificity and limit toxicity through the creation of logic-gated circuits. As we close out the month of love, the Cancer Research Catalyst staff (chiefly based in the City of Brotherly Love) is not so secretly admiring this… Continue reading Editors’ Picks, February 2025: Improving CAR T, Studying Breast Cancer Risk, and More