Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu… Continue reading Epstein-Barr virus LMP1 enhances levels of large extracellular vesicle-associated PD-L1
Tag: Oncogenic Viruses
Epstein-Barr virus-encoded miR-BART11-3p modulates the DUSP6-MAPK axis to promote gastric cancer cell proliferation and metastasis
Ahronian LG, Sennott EM, Van Allen EM, Wagle N, Kwak EL, Faris JE, Godfrey JT, Nishimura K, Lynch KD, Mermel CH, Lockerman EL, Kalsy A, Gurski JM, Bahl S, Anderka K, Green LM, Lennon NJ, Huynh TG, Mino-Kenudson M, Getz G, Dias-Santagata D, Iafrate AJ, Engelman JA, Garraway LA, Corcoran RB. 2015. Clinical acquired resistance… Continue reading Epstein-Barr virus-encoded miR-BART11-3p modulates the DUSP6-MAPK axis to promote gastric cancer cell proliferation and metastasis
Early findings suggest clinical and lab-based approach critical to tracking head and neck cancer recurrence
AI SummaryEarly findings from two studies provide insights into potential methods for earlier detection and prediction of recurrence in HPV-positive head and neck cancer.Early findings of two studies shed light on new ways to anticipate recurrence in HPV-positive head and neck cancer sooner.
HIV-1 reverse transcriptase stability correlates with Gag cleavage efficiency: reverse transcriptase interaction implications for modulating protease activation
Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1 .
CDK8 inhibitors antagonize HIV-1 reactivation and promote provirus latency in T cells
INTRODUCTIONThe ability of HIV-1 to persist within infected cells as an integrated provirus, even during suppressive antiretroviral therapy (ART), represents the main barrier to achieve ART-free HIV remission or cure (1, 2). Various strategies to inactivate or eliminate latent viral reservoirs have been proposed, many of which involve approaches to modulate proviral expression (1, 3).… Continue reading CDK8 inhibitors antagonize HIV-1 reactivation and promote provirus latency in T cells
[Obituary] Harald zur Hausen
The German Nobel Laureate in Medicine, who discovered the role of human papillomavirus in causing cervical cancer, died