Research shows that HPV accounts for 70% of all throat cancers, but only one-third of the public is aware that HPV causes throat cancer.
Tag: Oncogenic Viruses
TWiV 1173: Holy Cow! Convergent evolution!
TWiV reviews nominees to head NIH, FDA, and CDC, cervical cancer decline following HPV vaccination, local dengue in Texas, human isolate of H5N1 virus is transmissible and virulent in animal models, and shared mechanisms of immune evasion among animal and bacterial viruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey… Continue reading TWiV 1173: Holy Cow! Convergent evolution!
Analysis of the ubiquitin-modified proteome identifies novel host factors in Kaposi’s sarcoma herpesvirus lytic reactivation
Mechanisms underlying the compromised clinical efficacy of interferon in clearing HBV
Hepatitis B virus (HBV) is a hepatotropic DNA virus that can cause acute or chronic hepatitis, representing a significant global health concern. By 2019, approximately 296 million individuals were chronically … Continue reading on BioMed Central
Evaluation of ALKBH2 and ALKBH3 gene regulation in patients with adult T-cell leukemia/lymphoma
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus that causes malignant adult T-cell leukemia/lymphoma (ATL). Patients infected with HTLV-1 are considered HTLV-1 carriers, and a small proportio… Continue reading on BioMed Central
The viral puzzle of why humans are susceptible to hepatitis B virus, but monkeys are not
Hepatitis B virus (HBV) has a narrow host range, mainly infecting hominoids. A new study reveals the structural differences in the liver cell receptor (NTCP) between humans and monkeys, explaining why HBV infects humans but not monkeys. This marks a significant medical breakthrough, by identifying new molecular targets for anti-HBV drug development for treating hepatitis… Continue reading The viral puzzle of why humans are susceptible to hepatitis B virus, but monkeys are not
Editors’ Picks, November 2024: Cervical Cancer in Native Americans, Nanovaccines, and More
The cover of Cancer Prevention Research was adopted from a figure in the study that showed the abundance of bacteria in the vaginal microbiome. As we head into the holiday season, Cancer Research Catalyst has tantalizing teasers in the form of science stocking stuffers straight from our November edition of Editors’ Picks. This month, the… Continue reading Editors’ Picks, November 2024: Cervical Cancer in Native Americans, Nanovaccines, and More
Features of hyperinflammation link the biology of EBV infection and cytokine storm syndromes
Obtaining HBV core protein VLPs carrying SARS-CoV-2 nucleocapsid conserved fragments as vaccine candidates
The Hepatitis B core antigen (HBcAg) has been used as a carrier of several heterologous protein fragments based on its capacity to form virus-like particles (VLPs) and to activate innate and adaptive immune re… Continue reading on BioMed Central
Sintilimab plus HPV vaccine for recurrent or metastatic cervical cancer
Purpose Recurrent or metastatic cervical cancer (r/m CC) presents limited treatment options for patients failed or progressed quickly following first-line therapy. This study investigated the potential of sintilimab with a prophylactic human papillomavirus (HPV) quadrivalent vaccine as a second-line treatment for r/m CC. Methods In this phase 2 clinical trial, patients with r/m CC previously… Continue reading Sintilimab plus HPV vaccine for recurrent or metastatic cervical cancer