Tag: Oncogenic Viruses
Human papillomavirus infection of the fallopian tube as a potential risk factor for epithelial ovarian cancer
AI SummaryThe article discusses the potential role of human papillomavirus (HPV) infection in the fallopian tube as a risk factor for epithelial ovarian cancer (EOC). The study analyzed DNA samples from EOC patients and found that HPV16 DNA was detected in one-third of the fallopian tube and tumor samples from EOCs, with a higher prevalence… Continue reading Human papillomavirus infection of the fallopian tube as a potential risk factor for epithelial ovarian cancer
Clinical validation of a tissue-agnostic genome-wide methylome enrichment MRD assay for head and neck malignancies
AI SummaryThis article discusses the need for a tissue-agnostic genome-wide methylome enrichment MRD assay for detecting molecular residual disease in patients with head and neck malignancies. The test is crucial for identifying patients at risk of recurrence within the first two years after treatment, as outcomes for head and neck cancer patients remain poor despite… Continue reading Clinical validation of a tissue-agnostic genome-wide methylome enrichment MRD assay for head and neck malignancies
Fibroblast stromal support model for predicting human papillomavirus-associated cancer drug responses
Hep C: We’re closer than ever to solving mystery of deadly virus
AI SummaryThis article discusses a new study that maps the protein complex that allows the hepatitis C virus to infect cells. With 300,000 deaths annually from hepatitis C, understanding this protein complex could lead to the development of an effective vaccine. This research brings us closer to solving the mystery of this deadly virus.Around 300,000… Continue reading Hep C: We’re closer than ever to solving mystery of deadly virus
The polymorphism analysis and therapy vaccine target epitopes screening of HPV-35 E6 E7 among the threaten α-9 HPV in Sichuan area
AI SummaryThis article focuses on the analysis of polymorphism and vaccine target epitopes of HPV-35 E6 E7, a type of HR-HPV in the α-9 group. Persistent infection of HR-HPV is linked to cervical cancer and SIL. The study aims to identify potential vaccine targets in the Sichuan area.High-risk human papilloma virus (HR-HPV) persistent infection is… Continue reading The polymorphism analysis and therapy vaccine target epitopes screening of HPV-35 E6 E7 among the threaten α-9 HPV in Sichuan area
[ASAP] Rational Design, Synthesis, and Structure–Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836
The Lysine Acetyltransferase PCAF Functionally Interacts with Estrogen Receptor Alpha in the Hippocampus of Gonadally Intact Male–But Not Female–Rats to Enhance Short-Term Memory
AI SummaryThe study explores the interaction between the lysine acetyltransferase PCAF and estrogen receptor alpha (ERα) in the hippocampus of male rats in enhancing short-term memory (STM). The research indicates that PCAF, known for its role in long-term memory (LTM) through epigenetic processes, also influences STM possibly through nongenomic ER activity. The interaction was specific… Continue reading The Lysine Acetyltransferase PCAF Functionally Interacts with Estrogen Receptor Alpha in the Hippocampus of Gonadally Intact Male–But Not Female–Rats to Enhance Short-Term Memory
Gemcitabine, carboplatin, and Epstein Barr virus-specific autologous cytotoxic T lymphocytes for recurrent or metastatic nasopharyngeal carcinoma: VANCE, an international randomized Phase 3 trial
AI SummaryThe content discusses a Phase 3 trial called VANCE, which examines the use of a combination of gemcitabine, carboplatin, and Epstein-Barr virus-specific autologous cytotoxic T lymphocytes in patients with recurrent or metastatic nasopharyngeal carcinoma (R/M NPC). The study aims to determine if this chemo-immunotherapy strategy is more effective and improves quality of life compared… Continue reading Gemcitabine, carboplatin, and Epstein Barr virus-specific autologous cytotoxic T lymphocytes for recurrent or metastatic nasopharyngeal carcinoma: VANCE, an international randomized Phase 3 trial
[News] Continued suboptimal HPV vaccine coverage in the USA
AI SummaryThe analysis by the US CDC showed that improvements in routine coverage of the HPV vaccine in the USA have stalled since the COVID-19 pandemic. The study looked at data from 2023, which revealed that only 61.4% of adolescents aged 13-17 were up to date with the full HPV vaccine schedule, a slight decrease… Continue reading [News] Continued suboptimal HPV vaccine coverage in the USA