Seeing more in expansion microscopy

In biology, seeing can lead to understanding, and researchers in Edward Boyden’s lab at MIT’s McGovern Institute are committed to bringing life into sharper focus. With a pair of new methods, they are expanding the capabilities of expansion microscopy—a high-resolution imaging technique the group introduced in 2015—so researchers everywhere can see more when they look… Continue reading Seeing more in expansion microscopy

Abuse potential and analgesic efficacy of intravenous hydromorphone bolus administration among hospitalized patients with cancer pain: A double‐blind, double dummy, randomized crossover trial

Abstract Background There is much concern that opioids administered as intravenous (iv) bolus for pain relief may inadvertently increase their risk for abuse. However, there is insufficient data to support this. The authors compared the abuse liability potential, analgesic efficacy, and adverse effect profile of fast (iv push) versus slow (iv piggyback) administration of iv… Continue reading Abuse potential and analgesic efficacy of intravenous hydromorphone bolus administration among hospitalized patients with cancer pain: A double‐blind, double dummy, randomized crossover trial