A striking 81% of participants with probable dementia were unaware of their diagnosis, with Mexican American participants showing significantly higher rates of lack of awareness. Medscape Medical News
Tag: Neural Diseases and Disorders
Updated AD Guidelines Chart the Full Diagnostic Journey
Expanded clinical practice guidelines aim to empower all clinicians, regardless of specialty or practice setting to evaluate suspected Alzheimer’s disease. Medscape Medical News
Can Sea Lions Expand Our Knowledge of Epilepsy?
The experimental treatment used to treat the prolonged seizures of a sea lion may offer insights into treatment approaches that can help humans. Medscape Medical News
SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
Alzheimer’s Disease (AD) is a neurodegenerative disease with drastically altered astrocytic metabolism. Astrocytic GABA and H2O2 are associated with memory impairment in AD and synthesized through the Monoamine O…
Losing Your Mind Trying to Understand the BP-Dementia Link
Cardiologist Christopher Labos reviews the data on blood pressure control and dementia in the context of recent studies suggesting that discontinuing antihypertensives may slow cognitive decline. theheart.org on Medscape
US Dementia Cases Projected to Double Within 40 Years
The number of US adults who will develop dementia each year is projected to increase from approximately 514,000 in 2020 to about1 million in 2060, new research shows. Medscape Medical News
Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis
Astrocytes, the most abundant glial cell type in the brain, will convert into the reactive state in response to proteotoxic stress such as tau accumulation, a characteristic feature of Alzheimer’s disease (AD)…
Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis
Ischemic stroke (IS) is a common cerebrovascular disease. Although the formation of atherosclerosis, which is closely related to oxidative stress (OS), is associated with stroke-related deaths. However, the ro…
The Year in Parkinson’s Disease 2024
Drs Indu Subramanian and Alfonso Fasano discuss some of the 2024 highlights in Parkinson’s disease research, including a paradigm shift in diagnosis and the potential role of GLP-1s. Medscape Neurology
Dementia Risk Higher for Stroke Survivors
Dementia risk is nearly 80% higher in stroke survivors than in those without stroke, with risk declining within 1 year but remaining elevated for up to 20 years, data show. Medscape Medical News