AI SummaryA 14-year-old girl was diagnosed with nonepileptic events after a diagnostic evaluation for recurrent abdominal pain. However, her long-term EEG recording revealed normal developmental variants that should be recognized to avoid misdiagnosis.A 14-year-old girl presented to the epilepsy monitoring unit for diagnostic evaluation of recurrent episodic abdominal pain. During the admission, multiple typical episodes… Continue reading Teaching NeuroImage: Pictures of Health in Pediatric EEG
Tag: Neural Diseases and Disorders
Early Treatment for Multiple Sclerosis: Time Is Brain
AI SummaryAdvancements in clinical trials have resulted in many treatment options for MS, but the best practices for using these treatments are still being researched and debated, particularly in regards to when and how to start disease-modifying therapies.Over the past decades, clinical trial successes have led to a profusion of treatment options for multiple sclerosis… Continue reading Early Treatment for Multiple Sclerosis: Time Is Brain
News & views: anti-amyloid antibodies and novel emerging approaches to Alzheimer’s disease in 2023
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APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
AI SummaryThe text discusses the role of microglial APOE4 in Alzheimer’s disease (AD) and its impact on the microglial response to neurodegeneration. The study shows that deletion of microglial APOE4 improves neuroprotection and decreases pathology in mouse models. It also explores the molecular mechanisms involved, such as LGALS3 signaling and ITGB8-TGFβ pathway. The findings suggest… Continue reading APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Hyperbaric Oxygen Therapy for TBI: Wishful Thinking?
AI SummaryA recent review prompted a neurologist to revisit a treatment he trained in decades ago for traumatic brain injury.A recent review recommending HBOT for traumatic brain injury prompted this neurologist to revisit a treatment he trained in decades ago. Medscape Neurology
[ASAP] Resilience to Pain-Related Depression in σ1 Receptor Knockout Mice Is Associated with the Reversal of Pain-Induced Brain Changes in Affect-Related Genes
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Artificial Sweeteners in Foods Tied to Increased Depression Risk
AI SummaryRecent data shows that there may be a connection between consuming ultraprocessed food, specifically artificial sweeteners, and a higher risk of depression.New data suggest a link between ultraprocessed food, particularly artificial sweeteners, and increased depression risk. Medscape Medical News
Anxiety, Depression May Ease After Ablation Cuts AF Burden
AI SummaryResearchers acknowledge that there may be a placebo effect from AF ablation, but it is likely not the main cause of psychological benefits.One can’t say there is no placebo effect from AF ablation, but if there is, it’s probably not the main driver of psychological benefit, say researchers. Medscape Medical News
[Comment] A genetic basis for the severity of multiple sclerosis
AI SummaryMultiple sclerosis is a neurodegenerative disorder with variable outcomes. Over 200 genetic variants have been linked to the development of multiple sclerosis, mainly in genes expressed by immune cells. Current therapies target lymphocytes but some patients still experience neurological disability.Multiple sclerosis is an autoimmune, neurodegenerative disorder with highly variable long-term outcomes.1 More than 200… Continue reading [Comment] A genetic basis for the severity of multiple sclerosis
[Review] Prevention of perioperative stroke in patients undergoing non-cardiac surgery
AI SummaryApproximately 300 million adults undergo non-cardiac surgery yearly, resulting in a significant number of stroke cases. Perioperative stroke has a high mortality rate and often leads to severe disability. Covert brain infarctions, more common than overt strokes, contribute to postoperative delirium, cognitive decline, and future cerebrovascular events. Older age, hypertension, atrial fibrillation, and especially… Continue reading [Review] Prevention of perioperative stroke in patients undergoing non-cardiac surgery