AI SummaryThe article examines the relationship between gut microbiota and multiple sclerosis through a scientometric analysis from 2010 to 2023. Multiple sclerosis is a chronic inflammatory disease of the central nervous system influenced by genetic and environmental factors. The human gut microbiota plays a critical role in bidirectional communication with the CNS. Despite previous studies… Continue reading The role of the gut microbiota in multiple sclerosis: A scientometric analysis reveals key research trends
Tag: Multiple Sclerosis
Study reveals ways in which 40Hz sensory stimulation may preserve brain’s “white matter”
AI SummaryIn a study conducted by MIT researchers, it was found that 40Hz sensory stimulation can preserve myelination in the brain, which is essential for optimal brain function. This stimulation helps protect the white matter in the brain and sustain the insulation of axons. It also aids in maintaining neural circuit connections, reducing inflammation, promoting… Continue reading Study reveals ways in which 40Hz sensory stimulation may preserve brain’s “white matter”
New histone tag discovery offers hope for myelin repair in neurodegenerative diseases
AI SummaryThe research study by CUNY ASRC has discovered a new histone tag, lysine 8 acetylation on histone H4, in adult OPCs that may lead to innovative therapies for myelin repair in neurodegenerative diseases. This finding addresses the challenge of translating neonatal OPC research into adult brain therapies and offers potential new treatments for conditions… Continue reading New histone tag discovery offers hope for myelin repair in neurodegenerative diseases
Smoldering Inflammation in MS: Insights and Emerging Therapies
Drs Michael Kornberg and Pavan Bhargava discuss the effects of smoldering inflammation in disease progression and potential new therapies. Consortium of Multiple Sclerosis Centers
Understanding Astrocytes’ Role in MS & Revealing a Biomarker
AI SummaryThis article discusses the role of astrocytes in multiple sclerosis (MS) and the discovery of a potential biomarker called Anastellin. Researchers found that MS patients have low levels of TIMP-1 expression in astrocytes, leading to the release of Anastellin, which creates a toxic environment in the brain. This peptide can also block a receptor… Continue reading Understanding Astrocytes’ Role in MS & Revealing a Biomarker
Acute Clinical Events Identified as Relapses With Stable MRI in Multiple Sclerosis
AI SummaryThis study investigates clinical events in multiple sclerosis that are identified as relapses despite a lack of changes in MRI scans, specifically looking at T2 lesions and gadolinium-enhanced T1 lesions. The aim is to understand the relationship between clinical symptoms and MRI findings in MS relapses.This cohort study evaluates clinical events identified as relapses… Continue reading Acute Clinical Events Identified as Relapses With Stable MRI in Multiple Sclerosis
From the Bench, July 2024: Fighting Chemo Brain With Light, Controlling Cancer Cell Death, and More
AI SummaryThis piece highlights several cutting-edge cancer research studies, including the use of audiovisual pulses to combat “chemo brain,” the development of a system to control cancer cell death pathways, a virus-inspired delivery system for treating lung tumors, a more accurate humanized mouse model, the creation of “mini-colons” to study cancer initiation, and a cancer… Continue reading From the Bench, July 2024: Fighting Chemo Brain With Light, Controlling Cancer Cell Death, and More
WVU researchers explore immune cell interactions in multiple sclerosis
AI SummaryThe article discusses a study by a West Virginia University immunologist on how the interaction between two types of immune cells in the central nervous system contributes to the development of multiple sclerosis (MS). The research aims to identify proteins that regulate this interaction to potentially develop new strategies for treating MS and other… Continue reading WVU researchers explore immune cell interactions in multiple sclerosis
Drug target identified for diseases associated with leukemia-causing virus
AI SummaryThis study identifies a potential drug target for diseases linked to the human T-cell leukemia virus type 1, including a specific type of leukemia and a disease resembling multiple sclerosis. This discovery could lead to new treatment options for these conditions.A team of researchers found a potential new target for treating diseases associated with… Continue reading Drug target identified for diseases associated with leukemia-causing virus
Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimers Disease and Multiple Sclerosis
AI SummaryThe article explores the effects of TREM2 agonist antibodies in preclinical models of Alzheimer’s disease and multiple sclerosis. Three different antibodies were tested in mouse models, with results showing limited impact on disease pathology in Alzheimer’s models and disruption of injury resolution in multiple sclerosis models. The study emphasizes the importance of dose timing… Continue reading Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimers Disease and Multiple Sclerosis