AI SummaryA trial suggests that people with multiple sclerosis and obesity can achieve weight loss and improve mobility and quality of life with a specialized program.People with multiple sclerosis and obesity can achieve substantial weight loss, leading to improved mobility and quality of life, with a specially designed program, new trial results suggest. Medscape Medical… Continue reading MS-Tailored Weight Loss Program Achieves Meaningful Results
Tag: Multiple Sclerosis
Ocrelizumab Benefit Confirmed in Older Patients With MS
The relapse benefit of ocrelizumab in multiple sclerosis is confirmed for the first time in patients 60 and older starting therapy, say researchers in findings they hope will inform choices. Medscape Medical News
AI Tool Reveals MS Drug Interactions, Offers Safer Options
Clinicians prescribing a drug for patients with multiple sclerosis who are on multiple treatments may in future use AI to identify potential interactions and suggest safer options, new data suggest. Medscape Medical News
[Comment] Radiologically isolated syndrome: knowns and unknowns
AI SummaryThe term Radiologically Isolated Syndrome (RIS) is used to describe individuals with MRI findings suggestive of multiple sclerosis but who do not exhibit any symptoms of the disease. As MRI scanners become more accessible and scanning methods improve, there is expected to be an increase in the number of people diagnosed with RIS.Radiologically isolated… Continue reading [Comment] Radiologically isolated syndrome: knowns and unknowns
[Personal View] Radiologically isolated syndrome
Individuals can be deemed to have radiologically isolated syndrome (RIS) if they have incidental demyelinating-appearing lesions in their brain or spinal cord that are highly suggestive of multiple sclerosis but their clinical history does not include symptoms consistent with multiple sclerosis. Data from international longitudinal cohorts indicate that around half of people with RIS will… Continue reading [Personal View] Radiologically isolated syndrome
Clinical, Radiologic, and Immunologic Features of Patients With CTLA4 Deficiency With Neurologic Involvement
Objectives CTLA4 deficiency (CTLA4d) is a disease with multisystem autoimmune features, including neurologic manifestations. We aimed to describe neurologic involvement in these patients. Methods We performed a cross-sectional observational study using the French Reference Centre for Primary Immunodeficiencies (CEREDIH) registry plus a surveillance in national society networks. Participants with confirmed CTLA4d and neurologic involvement were… Continue reading Clinical, Radiologic, and Immunologic Features of Patients With CTLA4 Deficiency With Neurologic Involvement
Internet CBT Eases Depressive Symptoms in Multiple Sclerosis
AI SummaryInternet-based cognitive behavioral therapy has been found to effectively reduce depressive symptoms in patients with MS, according to a recent phase 3 trial. Summary unavailable.Internet-based cognitive behavioral therapy significantly reduces depressive symptoms in patients with MS, results from a multisite, phase 3, randomized trial show. Medscape Medical News
Teriflunomide and Time to Clinical Multiple Sclerosis in Radiologically Isolated Syndrome
This randomized clinical trial investigates the efficacy of the disease-modifying treatment, teriflunomide, in extending the time to a first clinical event in patients with preclinical multiple sclerosis.
Vaccines and the Risk of Hospitalization for Multiple Sclerosis Flare-Ups
This cohort study examines whether different vaccines are associated with multiple sclerosis flare-ups requiring hospitalization.
Error in Figures
In the Original Investigation titled “Rituximab vs Ocrelizumab in Relapsing-Remitting Multiple Sclerosis,” published online June 12, 2023, there were errors in the point estimate and error bars in Figure 2A and in the graph labels in Figure 4. The point estimate and error bars were adjusted for accuracy, and the graph labels were switched, respectively.… Continue reading Error in Figures