A cool path to disease deceleration

In 2020, Kathrin “Kat” Kajderowicz’s father passed away from lung cancer. Kajderowicz was in charge of her father’s health care for as long as she can remember. While he suffered from various cardiovascular issues for several years, it wasn’t until the beginning of the Covid-19 pandemic that he was diagnosed with late-stage metastatic small-cell lung… Continue reading A cool path to disease deceleration

Outdoor air pollution may increase non-lung cancer risk in older adults

Chronic exposure to fine particulate air pollutants (PM2.5) and nitrogen dioxide (NO2) may increase non-lung cancer risk in older adults, according to a new study. In a cohort study of millions of Medicare beneficiaries, the researchers found that exposures to PM2.5 and NO2 over a 10-year period increased the risk of developing colorectal and prostate… Continue reading Outdoor air pollution may increase non-lung cancer risk in older adults

Circulating immune cell dynamics as outcome predictors for immunotherapy in non-small cell lung cancer

The use of immune checkpoint inhibitors (ICIs) continues to transform the therapeutic landscape of non-small cell lung cancer . The importance of this cancer ‘macroenvironment can be deciphered by comprehensive analysis of peripheral blood immune cell subsets, has been demonstrated in several cutting-edge preclinical reports, and is corroborated by intriguing data emerging from ICI-treated patients… Continue reading Circulating immune cell dynamics as outcome predictors for immunotherapy in non-small cell lung cancer

Chronic immune-related adverse events in patients with cancer receiving immune checkpoint inhibitors: a systematic review

Immune-related adverse events (irAEs) are toxicities resulting from use of immune checkpoint inhibitors (ICIs) These side effects persist in some patients despite withholding therapy and using immunosuppressive and immune-modulating agents . The most common ICIs delivered were pembrolizumab (24%) and nivolumabs (37%) Most patients (75%) had metastatic disease and the primary cancer site was melanoma… Continue reading Chronic immune-related adverse events in patients with cancer receiving immune checkpoint inhibitors: a systematic review

Error in Abstract

The Original Investigation titled “Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios,” published May 8, 2023, was corrected to change “higher eGFR” to “lower eGFR” in the second sentence of the Results section of the abstract.