AI SummaryWe cannot summarize the provided text as it is a list of authors and affiliations, likely from a research paper or publication. It does not contain any specific information or main points that can be summarized.Li Y, Wang X, Blau DM, Caballero MT, Feikin DR, Gill CJ, Madhi SA, Omer SB, Simões EAF, Campbell… Continue reading Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope
Tag: Lipid and Membrane Biochemistry
Synaptotagmin 1-triggered lipid signaling facilitates coupling of exo- and endocytosis
Synaptic exocytosis and endocytosis are of prime importance for brain function. How a neuronal synapse “knows” how many synaptic vesicles have fused is essentially unknown. Bolz et al. identify here a lipid-based mechanism for the coupling of exocytic vesicle fusion to synaptic vesicle endocytosis via Synaptotagmin 1.
[ASAP] Motility of Synthetic Cells from Engineered Lipids
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The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus
AI SummaryThe risk of dementia increases with age. Understanding the biochemical changes in the aging brain can help find ways to prevent neurodegeneration.The risk for dementia increases exponentially from the seventh decade of life. Identifying and understanding the biochemical changes that sensitize the ageing brain to neurodegeneration will provide new opport…
AHA Reviews Impact of Aggressive LDL Lowering on the Brain
AI SummaryA new statement says that there is no evidence linking aggressive cholesterol-lowering to cognitive impairment or hemorrhagic stroke.The preponderance of evidence does not support the conclusion that aggressive cholesterol-lowering is associated with cognitive impairment or hemorrhagic stroke, a new statement concludes. Medscape Medical News
[ASAP] Controlling the Chameleonic Behavior and Membrane Permeability of Cyclosporine Derivatives via Backbone and Side Chain Modifications
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[ASAP] Differences and Similarities of the Intravenously Administered Lipid Nanoparticles in Three Clinical Trials: Potential Linkage between Lipid Nanoparticles and Extracellular Vesicles
AI SummaryI cannot summarize the text as the given information is a DOI (Digital Object Identifier). It is typically used to identify and locate a specific article in a scholarly journal. Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.3c00547
Conserved structures of ESCRT-III superfamily members across domains of life
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Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine
The molecular checkpoints in ILC2s that determine whether to launch a proinflammatory response are unknown. Zang et al. show that the dynamic regulation of RXRγ expression and its mediated lipid metabolic states function as a cell-intrinsic molecular checkpoint that confers the activation threshold of ILC2s in the small intestine.
Axon Initial Segment GABA Inhibits Action Potential Generation throughout Periadolescent Development
AI SummaryGABA at the axon initial segment inhibits action potential initiation in neurons, regardless of whether chloride flows out or into the cell.Neurons are remarkably polarized structures: dendrites spread and branch to receive synaptic inputs while a single axon extends and transmits action potentials (APs) to downstream targets. Neuronal polarity is maintained by the axon… Continue reading Axon Initial Segment GABA Inhibits Action Potential Generation throughout Periadolescent Development