Tag: Lipid and Membrane Biochemistry
[ASAP] The Transformative Potential of Lipid Nanoparticle–Protein Corona for Next-Generation Vaccines and Therapeutics
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.3c00479
AHA Updates CPR Guidelines on Cardiac Arrest After Poisoning
AI SummaryThe AHA update now allows the use of venoarterial ECMO for patients who don’t respond to other treatments.The AHA update now includes the use of venoarterial extracorporeal membrane oxygenation for patients whose condition is refractory to other treatments. Medscape Medical News
[ASAP] Enhancement of Anti-inflammatory Effects of Synthetic High-Density Lipoproteins by Incorporation of Anionic Lipids
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.3c00175
Thousands of programmable DNA-cutters found in algae, snails, and other organisms
AI SummaryScientists at MIT’s McGovern Institute have identified thousands of programmable DNA-cutting enzymes called Fanzors, which are found in a diverse range of species. Fanzors are RNA-guided enzymes that can be programmed to cut DNA at specific sites, similar to the widely used gene-editing system CRISPR. This discovery provides scientists with a wide set of… Continue reading Thousands of programmable DNA-cutters found in algae, snails, and other organisms
Cleavage of VAMP2/3 Affects Oligodendrocyte Lineage Development in the Developing Mouse Spinal Cord
AI SummaryCleavage of VAMP2/3 proteins impairs the development of oligodendrocytes and myelination in mice. This study highlights the importance of VAMP2/3 in regulating the maturation of oligodendrocytes and myelin formation.In the developing and adult CNS, new oligodendrocytes (OLs) are generated from a population of cells known as oligodendrocyte precursor cells (OPCs). As they begin to… Continue reading Cleavage of VAMP2/3 Affects Oligodendrocyte Lineage Development in the Developing Mouse Spinal Cord
LDL-Lowering Tied to Lower First CVD Events in Patients 70+
AI SummaryElderly people benefit from LDL cholesterol-lowering therapy same as younger individuals.People 70 years of age and older taking LDL cholesterol-lowering therapy for primary prevention have the same reduction in major vascular events as their younger counterparts, new research confirms. Medscape Medical News
DNA segregation in mitochondria and beyond: insights from the trypanosomal tripartite attachment complex
Evaluation of Kdo-8-N3 Incorporation into Lipopolysaccharides of Various Escherichia coli strains
AI SummaryThe text describes the use of a compound called Kdo-8-N3 for metabolic labeling of lipopolysaccharide (LPS) structures on the cell membrane of Gram-negative bacteria. The authors explored the variability in LPS labeling using Kdo-8-N3 in different E. coli strains and serotypes. Different extents of labeling were observed, and the majority of labeled LPS was… Continue reading Evaluation of Kdo-8-N3 Incorporation into Lipopolysaccharides of Various Escherichia coli strains
Individual neurons mix multiple RNA edits of key synapse protein, study finds
AI SummaryA new study by neurobiologists at The Picower Institute for Learning and Memory reveals that RNA editing of a protein called complexin 7A can significantly affect how well it regulates the release of the neurotransmitter glutamate in neurons. The study found that individual neurons can have up to eight different editions of complexin 7A,… Continue reading Individual neurons mix multiple RNA edits of key synapse protein, study finds