AI SummaryThis article discusses the development of tubular scaffolds made from electrospun membranes that enhance bone regeneration in critical skull defects. These scaffolds, designed to mimic natural bone structures, provide an ideal environment for adipose-derived stem cells (rADSCs) to thrive and accelerate healing. By incorporating advanced materials such as polycaprolactone, PLGA, and nano-hydroxyapatite, researchers achieved… Continue reading Tubular scaffolds boost stem cell-driven bone regeneration in skull defects
Tag: Lipid and Membrane Biochemistry
[ASAP] Membrane-Targeting Amphiphilic Honokiol Derivatives Containing an Oxazole Moiety as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus
Genomic transfer via membrane vesicle: a strategy of giant phage phiKZ for early infection
Conformations of membrane human immunodeficiency virus (HIV-1) envelope glycoproteins solubilized in Amphipol A18 lipid-nanodiscs
[ASAP] Development of Integrin-Facilitated Bispecific Aptamer Chimeras for Membrane Protein Degradation
Unveiling the molecular mechanisms linking aging with neurodegenerative diseases
AI SummaryThe content provided discusses a recent study investigating the molecular mechanisms that connect aging with neurodegenerative diseases. The researchers focused on the protein PQBP3, which plays a role in stabilizing the nuclear membrane, and its implications in cellular senescence and neurodegeneration. The findings suggest that targeting PQBP3 could be a potential therapeutic strategy for… Continue reading Unveiling the molecular mechanisms linking aging with neurodegenerative diseases
[ASAP] Cell-Penetrating Peptides Translocate across the Plasma Membrane by Inducing Vesicle Budding and Collapse
Editors’ Picks, August 2024: ‘Colon Age’ Screening Recs, Stress From Violence, and More
AI SummaryThis article highlights the Editors’ Picks from August 2024 for the American Association for Cancer Research (AACR). The selections include topics such as a new metric called “Colon Age” for early-onset colorectal cancer screening, the relationship between exposure to neighborhood violence and glucocorticoid receptor signaling in lung tumors, and the development of a CD33-targeting… Continue reading Editors’ Picks, August 2024: ‘Colon Age’ Screening Recs, Stress From Violence, and More
[ASAP] Corannulene Amino Acid-Derived Water-Soluble Amphiphilic Buckybowls as Broad-Spectrum Membrane Targeting Antibacterial Agents
AI SummaryThis article discusses the development of water-soluble amphiphilic buckybowls derived from amino acids, specifically Corannulene, as antibacterial agents targeting cell membranes. These buckybowls have shown potential as broad-spectrum antibacterial agents.
[ASAP] Cholinized-Polymer Functionalized Lipid-Based Drug Carriers Facilitate Liver Fibrosis Therapy via Ultrafast Liver-Targeting Delivery
BiomacromoleculesDOI: 10.1021/acs.biomac.4c00691