Scientists have succeeded in controlling the structure and function of biological membranes with the help of ‘DNA origami’. The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic interventions. Thus, a very valuable instrument can be… Continue reading DNA nanorobots can alter artificial cells
Tag: Lipid and Membrane Biochemistry
Effect of tryptophan starvation on inclusion membrane composition and chlamydial-host interactions
Infection and Immunity, Ahead of Print.
Experts Forecast Cancer Research and Treatment Advances in 2025
Every new year brings excitement and anticipation for what might happen over the next 12 months. So, what’s in store for 2025 that could change the way we diagnose and treat cancer? What first-in-class therapeutics could offer new life-saving options to patients? What scientific discovery will have everyone talking? In 2024, we saw the approval… Continue reading Experts Forecast Cancer Research and Treatment Advances in 2025
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis
Science Immunology, Volume 10, Issue 103, January 2025.
Tongue cancer organoids reveal secrets of chemotherapy resistance
Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers. Using a large-scale library of TC organoids they developed, the researchers performed comprehensive comparative analyses of chemo-sensitive and chemo-resistant cells. Their efforts shed light on promising avenues toward new treatments for tongue cancer.
[ASAP] Macrophage Membrane-Cloaked ROS-Responsive Albumin Nanoplatforms for Targeted Delivery of Curcumin to Alleviate Acute Liver Injury
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.4c00808
Gut microbes and the body work together to regulate fat metabolism
Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University’s Ithaca campus. The human body has co-evolved with the beneficial microbes that live in the gut (termed the microbiota), resulting… Continue reading Gut microbes and the body work together to regulate fat metabolism
[ASAP] Pseudo-Phosphorylated Tau Forms Paired Helical Filaments in the Presence of High-Curvature Cholesterol-Containing Lipid Membranes
Scientists uncover key factors for starting autophagy in cells
Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks. This vital process prevents the formation of harmful aggregates and makes nutrients available again. A research team co-led by Prof. Dr. Claudine… Continue reading Scientists uncover key factors for starting autophagy in cells