AI SummaryMIT neuroscientists have discovered that the adult brain contains silent synapses, immature connections between neurons that remain inactive until they are recruited to help form new memories. About 30% of synapses in the adult mouse brain are silent, and the researchers believe this helps the brain continuously form new memories without modifying existing synapses.… Continue reading Silent synapses are abundant in the adult brain
Tag: Lipid and Membrane Biochemistry
Alzheimer’s risk gene undermines insulation of brain’s “wiring”
AI SummaryA new study published in Nature by an MIT-based team provides insight into how the APOE4 gene variant increases the risk for Alzheimer’s disease. The study shows that APOE4 disrupts the management of cholesterol in brain cells called oligodendrocytes, leading to a deficiency in the fatty insulation of neurons known as myelin, which impairs… Continue reading Alzheimer’s risk gene undermines insulation of brain’s “wiring”