Tag: Innate Immunity
Itch in elderly patients: Origin, diagnostics, management
Does pollen exposure influence innate immunity to SARS-CoV-2 in allergy or asthma?
Microbiota transplant to control inflammation in a patient with NLRC4 gain-of-function–induced disease
Intestinal Candida albicans overgrowth in IgA deficiency
IL-21 induces pyroptosis of Treg cells via Akt–mTOR–NLRP3–caspase 1 axis in eosinophilic chronic rhinosinusitis
Scientists discover how mutations in a language gene produce speech deficits
AI SummaryMutations in the gene Foxp2 have been linked to speech disorders, specifically apraxia. Researchers from MIT and National Yang Ming Chiao Tung University conducted a study on mice and found that these mutations disrupt the formation of dendrites and neuronal synapses in the brain, affecting the ability to produce high-frequency sounds. The mutations prevent… Continue reading Scientists discover how mutations in a language gene produce speech deficits
IgE receptor of mast cells signals mediator release and inflammation via adaptor protein 14-3-3ζ
Siglec-9 is an inhibitory receptor on human mast cells in vitro
A new peptide may hold potential as an Alzheimer’s treatment
AI SummaryMIT neuroscientists have discovered a peptide that can reverse neurodegeneration and other symptoms of Alzheimer’s disease by interfering with an enzyme called CDK5 that is overactive in Alzheimer’s patients. In mice, the peptide led to reductions in neurodegeneration, DNA damage, and improvements in cognitive abilities, leading researchers to believe it could serve as a… Continue reading A new peptide may hold potential as an Alzheimer’s treatment