The study aims to investigate the safety, immunogenicity, and potential efficacy of OVX836 at different doses . Vaccine demonstrated an observed protection level of 84%, which was further corroborated by a pooled analysis . The findings are particularly encouraging, as they approach the target efficacy for a universal influenza vaccine (>75%)
Tag: Influenza
TWiV 1033: Freediving with nanobodies and interferon
TWiV notes the passing of Harald zur Hausen, dengue breaking records in the Americas, inhibition of SARS-CoV-2 infection and inflammation by modulation of type I IFN, and an armed nanobody that protects mice against influenza A and B disease. Hosts: Vincent Racaniello, Kathy Spindler, and Angela Mingarelli Click arrow to playDownload TWiV 1033 (76 MB .mp3,… Continue reading TWiV 1033: Freediving with nanobodies and interferon
Influenza shows no seasonality in tropics, posing challenges for health care
In temperate climates, like North America and Europe, flu season starts in the fall, peaks in winter and ends in spring . Public health officials have generally assumed that influenza is also seasonal in tropical climates . But new research has found little evidence of a repeatable pattern in influenza cases in Vietnam .
The M2 proteins of bat influenza A viruses reveal atypical features compared to conventional M2 proteins
Co-evolution of immunity and seasonal influenza viruses
Abstract Seasonal influenza viruses cause recurring global epidemics by continually evolving to escape host immunity. The viral constraints and host immune responses that limit and drive the evolution of these viruses are increasingly well understood. However, it remains unclear how most of these advances improve the capacity to reduce the impact of seasonal influenza viruses… Continue reading Co-evolution of immunity and seasonal influenza viruses
Detection of human adenoviruses in influenza-negative patients with respiratory tract infections in Nanning, China
HAdV is associated with various clinical manifestations, including hepatitis,gastroenteritis, meningitis, cystitis, conjunctivitis, upper and lower respiratory tract infections, and myocarditis etc. [14,15,<a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" title="Chhabra P, Payne DC, Szilagyi PG et al. Etiology of viral gastroenteritis in children 16,17,18,19,20]. Moreover, HAdV infection spreads easily, is highly contagious in some cases, can cause… Continue reading Detection of human adenoviruses in influenza-negative patients with respiratory tract infections in Nanning, China