Highly pathogenic H5N1 avian influenza A virus (HPAI H5N1) remains a low risk to the general public, and public health experts in the United States believe that available treatments and vaccines, as well as those in development, are sufficient to prevent severe disease.
Tag: Influenza
Effect of Diabetes and Obesity on Influenza Outcomes
by Gertrud U. Rey Flu season is in full swing, and hospitalizations related to influenza virus infection are on the rise. During the 2009 “swine flu” pandemic it became evident that diabetes and obesity increase one’s risk for severe influenza disease, a correlation that was also later observed in the context of COVID-19. A series… Continue reading Effect of Diabetes and Obesity on Influenza Outcomes
Molecular epidemiological analysis of Influenza viruses in Influenza-like illness cases: a retrospective study in Chongqing Hi-Tech Zone, China (2021–2024)
To analyze the molecular epidemiological characteristics of influenza viruses in influenza-like cases in Chongqing Hi-Tech Zone, China, to provide data support and a scientific basis for optimizing influenza p… Continue reading on BioMed Central
Human ANP32A/B are SUMOylated and utilized by avian influenza virus NS2 protein to overcome species-specific restriction
Abstract Human ANP32A/B (huANP32A/B) poorly support the polymerase activity of avian influenza viruses (AIVs), thereby limiting interspecies transmission of AIVs from birds to humans. The SUMO-interacting motif (SIM) within NS2 promotes the adaptation of AIV polymerase to huANP32A/B via a yet undisclosed mechanism. Here we show that huANP32A/B are SUMOylated by the E3 SUMO ligase… Continue reading Human ANP32A/B are SUMOylated and utilized by avian influenza virus NS2 protein to overcome species-specific restriction
Zoonotic transmission of novel Influenza A variant viruses detected in Brazil during 2020 to 2023
Abstract Zoonotic infections (swine-human) caused by influenza A viruses (IAVs) have been reported and linked to close contact between these species. Here, we describe eight human IAV variant infections (6 mild and 2 severe cases, including 1 death) detected in Paraná, Brazil, during 2020–2023. Genomes recovered were closely related to Brazilian swIAVs of three major… Continue reading Zoonotic transmission of novel Influenza A variant viruses detected in Brazil during 2020 to 2023
TWiV 1178: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin deep dives into the whooping cough epidemic and bird flu in big cats, and in conjunction with your host Vincent Racaniello discusses the recent case of paralytic poliomyelitis in Israel, measles outbreaks and HHS campaign for vaccine safety campaign before reviewing the recent statistics on SARS-CoV-2 infection, the… Continue reading TWiV 1178: Clinical update with Dr. Daniel Griffin
TWiV 1177: Going to school for flu
At the School for Influenza in Brisbane, TWiV speaks with Kirsty, Erik and Rebecca about their careers and their research. Host: Vincent Racaniello Guests: Kirsty Short, Erik Karlsson, and Rebecca Cox Click arrow to playDownload TWiV 1177 (120 MB .mp3, 84 min) Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV… Continue reading TWiV 1177: Going to school for flu
TWiV 1176: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin continues his discussion of whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses how routine childhood immunizations especially that against poliovirus are threatened by Robert F Kennedy Jr and Aaron Siri, the origin of the SAR-CoV-2 virus and… Continue reading TWiV 1176: Clinical update with Dr. Daniel Griffin
New design could make seasonal influenza vaccinations more broadly effective
Stanford Medicine scientists have designed a way to make our seasonal influenza vaccinations more broadly effective and possibly to protect us from new flu variants with pandemic potential. In a study set to publish Dec. 20 in Science, they’ve shown in cultured human tonsil tissue that the method works. Flu season is upon us, and… Continue reading New design could make seasonal influenza vaccinations more broadly effective
Study shows drop in use of antiviral medications in young children with influenza
Despite national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a recent study reports an underuse of the treatment.