AI SummaryThe article discusses how monoclonal antibodies could offer a solution to antimicrobial resistance. A team at the University of Cambridge has developed a monoclonal antibody drug using genetically engineered mice to combat infections caused by the bacteria Acinetobacter baumannii, which is increasingly resistant to antibiotics and commonly found in hospitals, particularly in Asia. This… Continue reading Monoclonal antibodies could help provide an answer to antimicrobial resistance
Tag: Immunotherapy
ESMO 2024: Promising results in immunotherapy and antibody drug conjugates for gynecological cancers
AI SummaryThe content discusses promising results in immunotherapy and antibody drug conjugates for gynecological cancers presented at ESMO 2024. Studies show that adding immunotherapy to standard treatments benefits women with early-stage endometrial and cervical cancers. Additionally, a novel antibody drug conjugate targeting claudin 6 has shown positive antitumor activity in heavily pretreated patients with ovarian… Continue reading ESMO 2024: Promising results in immunotherapy and antibody drug conjugates for gynecological cancers
Long-term metastatic melanoma survival dramatically improves on immunotherapy, study finds
AI SummaryThis study highlights the significant improvement in long-term survival rates for patients with metastatic melanoma treated with immune checkpoint inhibitors. The landmark international trial showed that about half of the patients remained cancer-free for 10 years or more after treatment. This finding demonstrates the promising potential of immunotherapy in significantly improving outcomes for patients… Continue reading Long-term metastatic melanoma survival dramatically improves on immunotherapy, study finds
Monoclonal antibodies offer hope for tackling antimicrobial resistance
AI SummarySummary: Scientists believe that monoclonal antibodies, which are treatments created by cloning cells that produce antibodies, could be a promising solution for combating antimicrobial resistance.Monoclonal antibodies — treatments developed by cloning a cell that makes an antibody — could help provide an answer to the growing problem of antimicrobial resistance, say scientists.
Immunotherapy shows promise for men with specific types of prostate cancer
AI SummarySummary: Immunotherapy has shown promise in treating specific types of prostate cancer by slowing down disease progression in men with certain genetic characteristics. In a recent study, the progression of the disease was delayed by 33 months in these individuals.New research has shown that immunotherapy can be effective in treating prostate cancer in men… Continue reading Immunotherapy shows promise for men with specific types of prostate cancer
Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer
AI SummaryThis article discusses the results of an NCI trial indicating that administering pembrolizumab to patients after surgery for high-risk muscle invasive bladder cancer can double the median length of time they remain cancer-free compared to observation alone after surgery. This finding underscores the potential benefits of immunotherapy in treating high-risk bladder cancer patients.An NCI… Continue reading Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer
Conjugation of anti-HIV gp41 monoclonal antibody to a drug capable of targeting resting lymphocytes produces an effective cytotoxic anti-HIV immunoconjugate
Ipilimumab with Nivolumab in molecular-Selected patients with castration-resistant PRostate cancer: primary analysis of the Phase 2 INSPIRE trial
AI SummaryThis study focuses on the use of a combination of immune checkpoint inhibitors, Ipilimumab and Nivolumab, in molecularly-selected patients with castration-resistant prostate cancer. The aim is to investigate the efficacy and safety of this treatment approach in a subset of patients who display a more immunogenic profile. The results of this study could provide… Continue reading Ipilimumab with Nivolumab in molecular-Selected patients with castration-resistant PRostate cancer: primary analysis of the Phase 2 INSPIRE trial
The complexity of immune evasion mechanisms throughout the metastatic cascade
AI SummaryThis article discusses the immune evasion mechanisms used by cancer cells throughout the metastatic cascade. It explores how tumor cells adapt to survive in different environments encountered during metastasis, affecting organotropism. The interaction between tumor cells and the immune system is analyzed, emphasizing the creation of an immunosuppressive environment that promotes aggressive metastatic tumors.… Continue reading The complexity of immune evasion mechanisms throughout the metastatic cascade
NIH funds new research to combat emerging viruses
AI SummaryThe Albert Einstein College of Medicine has received funding from the NIH for a five-year project to develop vaccines and antibody-based therapies against emerging viruses. The project aims to build on lessons learned from COVID-19 by creating a base of critical knowledge about groups of similar viruses, allowing for the rapid development of specific… Continue reading NIH funds new research to combat emerging viruses