AI SummaryMIT neuroscientists have discovered a peptide that can reverse neurodegeneration and other symptoms of Alzheimer’s disease by interfering with an enzyme called CDK5 that is overactive in Alzheimer’s patients. In mice, the peptide led to reductions in neurodegeneration, DNA damage, and improvements in cognitive abilities, leading researchers to believe it could serve as a… Continue reading A new peptide may hold potential as an Alzheimer’s treatment
Tag: Immunodeficiency Disorders
Cohort-driven variant burden analysis and pathogenicity identification in monogenic autoinflammatory disorders
Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency
Prevalence of CFTR variants in primary immunodeficiency patients with bronchiectasis is an important modifying cofactor
The efficacy and safety of systemic corticosteroids as first line treatment for granulomatous lymphocytic interstitial lung disease
Five from MIT named 2023 Quad Fellows
AI SummaryFour MIT alumni and a Harvard-MIT doctoral student have been selected for the inaugural class of the Quad Fellowship, a joint initiative of the governments of Australia, India, Japan, and the United States. The fellowship aims to support exceptional individuals pursuing STEM graduate study in the United States and provides a $50,000 award for… Continue reading Five from MIT named 2023 Quad Fellows
Alzheimer’s risk gene undermines insulation of brain’s “wiring”
AI SummaryA new study published in Nature by an MIT-based team provides insight into how the APOE4 gene variant increases the risk for Alzheimer’s disease. The study shows that APOE4 disrupts the management of cholesterol in brain cells called oligodendrocytes, leading to a deficiency in the fatty insulation of neurons known as myelin, which impairs… Continue reading Alzheimer’s risk gene undermines insulation of brain’s “wiring”