AI SummaryAdvancements in HIV treatment have improved the lives of those with HIV, but longer lifespans come with new challenges related to age-related comorbidities. Organ transplantation can be a lifesaving option for those with end-stage organ diseases, regardless of their HIV status.After four decades of global research on HIV, advances in treatment have not only… Continue reading [Editorial] Transplant donation without discrimination
Tag: Immunodeficiency Disorders
P43-9 The treatment of Kaposi sarcoma: Chasing the progressive disease with the presentation of KICS
Kaposi Sarcoma is rare cancer associated with the coinfection of KSHV and HIV. However, the KSHV Inflammatory Cytokine Syndrome is even rarer diagnosed among Kaposi Sarcoma patients and has poor survival outcomes despite the treatment.
MO21-5 Chemotherapy regimen of Kaposi sarcoma in HIV/AIDS patients: A systematic review of randomized controlled trials
Kaposi sarcoma (KS) is one of common HIV-associated cancer. The availability of antiretroviral therapy (ART), liposomal doxorubicin, and several chemotherapy drugs have been reported the efficacy and tolerable side effect in case series and retrospective study. However, little is known the best chemotherapy regimen in this population. Thus, this systematic review intends to evaluate the… Continue reading MO21-5 Chemotherapy regimen of Kaposi sarcoma in HIV/AIDS patients: A systematic review of randomized controlled trials
HIV-1 Tat commandeers nuclear export of Rev-viral RNA complex by controlling hnRNPA2-mediated splicing
HIV-1 diverts cortical actin for particle assembly and release
Abstract Enveloped viruses assemble and bud from the host cell membranes. Any role of cortical actin in these processes have often been a source of debate. Here, we assessed if cortical actin was involved in HIV-1 assembly in infected CD4 T lymphocytes. Our results show that preventing actin branching not only increases HIV-1 particle release but… Continue reading HIV-1 diverts cortical actin for particle assembly and release
TWiV 1057: CMV-based HIV vaccine with Klaus Früh
Klaus Früh visits the Incubator to discuss his career and his work on cytomegalovirus-vectored vaccines which are unique in their ability to persistently maintain an immune shield of effector memory T cells, including highly unconventional MHC-II and MHC-E restricted CD8+ T cells. Host: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Klaus Früh Click arrow to playDownload… Continue reading TWiV 1057: CMV-based HIV vaccine with Klaus Früh
V3 tip determinants of susceptibility to inhibition by CD4-mimetic compounds in natural clade A human immunodeficiency virus (HIV-1) envelope glycoproteins
[Editorial] A new agenda to control tuberculosis
AI SummaryTuberculosis is still a major global health problem, especially in low-income and middle-income countries. The disease is becoming resistant to drugs, there are limited treatment options, and funding is not sufficient to combat it effectively.Tuberculosis remains one of the deadliest infectious diseases in the world, particularly in low-income and middle-income countries. An estimated global… Continue reading [Editorial] A new agenda to control tuberculosis
Epitope-dependent effect of long-term cART on maintenance and recovery of HIV-1-specific CD8+ T cells
Trends in HIV-1 pretreatment drug resistance and HIV-1 variant dynamics among antiretroviral therapy-naive Ethiopians from 2003 to 2018: a pooled sequence analysis
Ethiopia is among the highly HIV-affected countries, with reported 12,000 and 12,000 AIDS-related deaths and incidents as per reports from 2021. Although the country has made a promising progress in antiretrov… Continue reading on BioMed Central