Tag: Immunodeficiency Disorders
Reply to “Assessing the impact of HIV status on cervical cancer treatment outcomes in Botswana: A commentary”
Cancer, EarlyView.
Assessing the impact of HIV status on cervical cancer treatment outcomes in Botswana: A commentary
Cancer, EarlyView.
An antidiabetic helps the immune system recognize reservoirs of HIV
AI SummaryThis article discusses how the antidiabetic drug Metformin could aid in identifying and depleting reservoirs of HIV in individuals with the virus who are undergoing antiretroviral therapy. This could potentially lead to the complete elimination of the viral reservoir.Metformin, a drug used to treat type 2 diabetes, could help deplete the viral reservoir and… Continue reading An antidiabetic helps the immune system recognize reservoirs of HIV
Conformations of membrane human immunodeficiency virus (HIV-1) envelope glycoproteins solubilized in Amphipol A18 lipid-nanodiscs
MHC class I and II-deficient humanized mice are suitable tools to test the long-term antitumor efficacy of immune checkpoint inhibitors and T-cell engagers
AI SummaryThis article discusses the use of MHC class I and II-deficient humanized mice as tools to study the long-term efficacy of immune checkpoint inhibitors and T-cell engagers in cancer immunotherapy. The study explores different strategies to overcome xenograft-versus-host disease (xGVHD) in immunodeficient mice engrafted with human PBMCs and co-engrafted with tumor cells. The results… Continue reading MHC class I and II-deficient humanized mice are suitable tools to test the long-term antitumor efficacy of immune checkpoint inhibitors and T-cell engagers
Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env
Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics
Breadth and polyfunctionality of T cell responses to human cytomegalovirus in men who have sex with men: relationship with HIV infection and frailty
Human immunodeficiency virus-associated lymphomas: EHA–ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
AI SummaryThis clinical practice guideline focuses on the diagnosis, treatment, and follow-up of human immunodeficiency virus-associated lymphomas, specifically non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL). Despite a decrease in the incidence of HIV-associated NHL with the introduction of combination antiretroviral therapy (ART), NHL remains a common type of cancer in individuals living with HIV. Incidences… Continue reading Human immunodeficiency virus-associated lymphomas: EHA–ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆