AI SummaryThe study examined the association between a clinical diagnosis of traumatic encephalopathy syndrome (TES) and cognitive decline and brain volume changes in professional fighters. The results showed that fighters with a TES diagnosis had greater decreases in brain volume and cognitive decline compared to those without a TES diagnosis. The study suggests that TES… Continue reading Longitudinal Changes in Regional Brain Volumes and Cognition of Professional Fighters With Traumatic Encephalopathy Syndrome
Tag: Huntington’s Disease
Pearls & Oy-sters: CSF1R-Related Leukoencephalopathy With Spinal Cord Lesions Mimicking Multiple Sclerosis
AI SummaryThe text describes a case of an autosomal dominant neurologic disorder called CSF1R-related leukoencephalopathy, which causes various neurologic complications. The case report emphasizes the importance of considering adult-onset neurogenetic disorders in cases of white matter disease and using genetic testing for diagnosis and treatment decisions.CSF1R-related leukoencephalopathy is an autosomal dominant neurologic disorder causing microglial… Continue reading Pearls & Oy-sters: CSF1R-Related Leukoencephalopathy With Spinal Cord Lesions Mimicking Multiple Sclerosis
The Importance of Social Contact on Brain Atrophy Among Older Individuals
AI SummaryLoneliness and social isolation in older adults are serious public health risks, associated with negative health outcomes such as premature mortality, heart disease, depression, and cognitive decline. Studies have shown that social isolation is linked to brain atrophy and changes in brain volume. Summary unavailable.Loneliness and social isolation, or a lack of social contact… Continue reading The Importance of Social Contact on Brain Atrophy Among Older Individuals
Design and pilot implementation of the Achieving Cancer Equity through Identification, Testing, and Screening (ACE‐ITS) program in an urban underresourced population
AI SummaryThe ACE-ITS program aims to improve mammography maintenance and genetic risk assessment through patient navigation, education, and testing. The program has successfully conducted educational sessions, guided women to mammography screening, and performed genetic risk assessments.Abstract Introduction The Achieving Cancer Equity through Identification, Testing, and Screening (ACE-ITS) program is a community-engaged framework to improve mammography… Continue reading Design and pilot implementation of the Achieving Cancer Equity through Identification, Testing, and Screening (ACE‐ITS) program in an urban underresourced population
Turning the Page on Breast Cancer in Ohio: Lessons learned from implementing a multilevel intervention to reduce breast cancer mortality among Black women
AI SummaryTurning the Page on Breast Cancer (TPBC) is a program in Ohio that aims to reduce breast cancer mortality among Black women through multilevel interventions. They provide risk information and education through community events and a website, and have seen visits and usage of their website. TPBC partners with health care facilities and community-based… Continue reading Turning the Page on Breast Cancer in Ohio: Lessons learned from implementing a multilevel intervention to reduce breast cancer mortality among Black women
Concussions early in life tied to late life cognitive decline
AI SummaryHaving a concussion early in life is linked to lower thinking and memory scores in the long term, as well as a faster decline in these scores compared to individuals without concussions. This study, published in Neurology, focuses on twins.A study of twins shows that having a concussion early in life is tied to… Continue reading Concussions early in life tied to late life cognitive decline
The Hierarchy of Coupled Sleep Oscillations Reverses with Aging in Humans
AI SummaryOlder adults experience a decline in slow-wave sleep and the number of coupling events between slow waves and spindles, which impairs memory consolidation and predicts memory loss and brain atrophy. However, a study involving a large sample of individuals across different age groups found that, instead of abruptly changing, the coupling hierarchy gradually reverses… Continue reading The Hierarchy of Coupled Sleep Oscillations Reverses with Aging in Humans
Clinical Model Could Guide GBA Gene Testing in Parkinson’s
AI SummaryApplying a simple model of clinical and demographic features could help target genetic testing in Parkinson’s disease patients.Applying a simple model of clinical and demographic features associated with GBA mutation carrier status could help target genetic testing in patients with Parkinson’s disease, suggests a new study. Medscape Medical News
Associations of Dental Health With the Progression of Hippocampal Atrophy in Community-Dwelling Individuals: The Ohasama Study
Background and Objectives Although tooth loss and periodontitis have been considered risk factors of Alzheimer disease, recent longitudinal researches have not found a significant association with hippocampal atrophy. Therefore, this study aimed to clarify a longitudinal association between the number of teeth present (NTP) and hippocampal atrophy dependent on the severity of periodontitis in a… Continue reading Associations of Dental Health With the Progression of Hippocampal Atrophy in Community-Dwelling Individuals: The Ohasama Study
[Comment] Genome sequencing for the fast diagnosis of early-onset epilepsies
Technological advances have enabled genetic testing to become the first-line diagnostic investigation for individuals with early-onset epilepsies. A precise genetic diagnosis is essential because it has both personal and clinical utility and might enable timely administration of targeted treatments. Early genetic testing is, therefore, recommended in individuals with early-onset epilepsies, particularly developmental and epileptic encephalopathies.1… Continue reading [Comment] Genome sequencing for the fast diagnosis of early-onset epilepsies