Neuropsychiatric manifestations following chimeric antigen receptor T cell therapy for cancer: a systematic review of clinical outcomes and management strategies

Background Chimeric antigen receptor (CAR)-T cell therapy has emerged as a transformative modality in the treatment of patients with cancer. However, it is increasingly evident that this therapeutic approach is not without its challenges. The unique nature of CAR-T cells as living drugs introduces a distinct set of side effects. As the application of CAR-T… Continue reading Neuropsychiatric manifestations following chimeric antigen receptor T cell therapy for cancer: a systematic review of clinical outcomes and management strategies

[Comment] Autoimmune encephalitis: diagnostic challenges and tensions

Autoimmune encephalitis is an important and treatable cause of acute or subacute neurological disturbance. To optimise outcomes, several factors are crucial. First, education of the medical community is a priority, so that autoimmune encephalitis is considered in the differential diagnosis of diverse presentations such as new onset psychosis, seizures, and cognitive decline. Second, to support… Continue reading [Comment] Autoimmune encephalitis: diagnostic challenges and tensions