Ifrah Zawar is an Assistant Professor at the University of Virginia (Charlottesville, VA, USA). Born and raised in Pakistan, she obtained her medical degree from Aga Khan University (Karachi, Pakistan). She completed her neurology, epilepsy, and clinical neurophysiology training at the Cleveland Clinic (Cleveland, OH, USA) in 2021. Her main research interest is epilepsy, with… Continue reading [In Context] Ifrah Zawar
Tag: Epilepsy
[Articles] Evaluation of the feasibility, diagnostic yield, and clinical utility of rapid genome sequencing in infantile epilepsy (Gene-STEPS): an international, multicentre, pilot cohort study
Our findings support the feasibility of implementation of rapid genome sequencing in the clinical care of infants with new-onset epilepsy. Longitudinal follow-up is needed to further assess the role of rapid genetic diagnosis in improving clinical, quality-of-life, and economic outcomes.
Outcomes and Treatment Approaches for Super-Refractory Status Epilepticus
This study attempts to assess clinical characteristics, causes, outcomes, prognostic factors, and treatment approaches for patients with super-refractory status epilepticus.
Reframing Lesional Epilepsy as a Network Disease
The question why some brain lesions cause epilepsy whereas other do not has remained unanswered for the past century. Lesions are the leading identifiable cause of epilepsy in adults, especially in individuals older than 55 years. But, only 6% of those with stroke, 9% of those with intracerebral hemorrhage, and approximately 40% of those with… Continue reading Reframing Lesional Epilepsy as a Network Disease
Mapping Lesion-Related Epilepsy to a Human Brain Network
This case-control study evaluates the locations of epilepsy-associated lesions with respect to specific brain regions and networks.
Summer research offers a springboard to advanced studies
Doctoral studies at MIT aren’t a calling for everyone, but they can be for anyone who has had opportunities to discover that science and technology research is their passion and to build the experience and skills to succeed. For Taylor Baum, Josefina Correa Menéndez, and Karla Alejandra Montejo, three graduate students in just one lab… Continue reading Summer research offers a springboard to advanced studies
Incident Epilepsy, Antiseizure Medications, and Development of Osteoporosis
AI SummaryThis study assesses the relationship between epilepsy, antiseizure medications, and the risk of osteoporosis using population-based data. The study aims to quantify and analyze the independent hazards for osteoporosis associated with these factors.This cohort study uses population-based data to quantify and model the independent hazards for osteoporosis associated with epilepsy and antiseizure medications.
The New Era of Automated Electroencephalogram Interpretation
The electroencephalogram (EEG) is fundamental to the diagnosis and tailored management of epilepsy. Yet, its interpretation is far from being a plug-and-play process. Even among experts, variance in EEG interpretations and even epilepsy misdiagnosis are disappointingly common. Efforts to standardize criteria for EEG interpretation have helped, but they cannot eradicate the poor reliability of subjective… Continue reading The New Era of Automated Electroencephalogram Interpretation
Neuroscientists identify cells especially vulnerable to Alzheimer’s
AI SummaryNeurodegeneration in Alzheimer’s disease affects different brain regions unequally, with one of the first regions to show damage being the mammillary body in the hypothalamus. MIT researchers have identified a subset of neurons in the mammillary body that are most susceptible to neurodegeneration and hyperactivity, which leads to memory impairments. The findings suggest that… Continue reading Neuroscientists identify cells especially vulnerable to Alzheimer’s
Small studies of 40-hertz sensory stimulation confirm safety, suggest Alzheimer’s benefits
AI SummaryEarly-stage clinical studies have found that 40-hertz sensory stimulation was well-tolerated, with no serious adverse effects and produced neurological and behavioral benefits among participants with Alzheimer’s disease. The studies are preliminary and more extensive research is needed to determine the efficacy of 40-hertz sensory stimulation as a potential therapeutic for Alzheimer’s.A pair of early-stage… Continue reading Small studies of 40-hertz sensory stimulation confirm safety, suggest Alzheimer’s benefits