Tag: Enzyme Kinetics and Mechanisms
GluN3A and Excitatory Glycine Receptors in the Adult Hippocampus
The GluN3A subunit of N-methyl-D-aspartate receptors (NMDARs) plays an established role in synapse development, but its contribution to neural circuits in the adult brain is less clear. Recent work has demonstrated that in select cell populations, GluN3A assembles with GluN1 to form GluN1/GluN3A receptors that are insensitive to glutamate and instead serve as functional excitatory… Continue reading GluN3A and Excitatory Glycine Receptors in the Adult Hippocampus
[ASAP] Diffusion and Exchange Kinetics of Microparticle Formulations by Spatial Fourier Transform Fluorescence Recovery after Photobleaching with Patterned Illumination
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.4c00508
[ASAP] Versatile Peroxide Route-Based Kinetics-Controlled Coating Method to Construct Uniform Alkali Metal-Containing Fast Ionic Conductor Nanoshells
[ASAP] Ancillary Ligand Steric Effects and Cyclometalating Ligand Substituents Control Excited-State Decay Kinetics in Red-Phosphorescent Platinum Complexes
AI SummaryThis title suggests that the research focuses on how steric effects of ancillary ligands and substituents of cyclometalating ligands can impact the kinetics of excited-state decay in red-phosphorescent platinum complexes. This study likely explores how different ligand structures influence the efficiency of phosphorescent materials, which is crucial for applications in fields such as organic… Continue reading [ASAP] Ancillary Ligand Steric Effects and Cyclometalating Ligand Substituents Control Excited-State Decay Kinetics in Red-Phosphorescent Platinum Complexes
Ultrafast transient absorption spectra and kinetics of human blue cone visual pigment at room temperature
Replication kinetics of pathogenic Eurasian orthohantaviruses in human mesangial cells
AI SummaryThis article explores the replication kinetics of pathogenic Eurasian orthohantaviruses in human mesangial cells. Eurasian orthohantaviruses are known to cause hemorrhagic fever with renal syndrome (HFRS), which is characterized by acute kidney injury (AKI). The study aims to understand how these viruses replicate in human cells, potentially shedding light on the mechanisms behind HFRS… Continue reading Replication kinetics of pathogenic Eurasian orthohantaviruses in human mesangial cells
[ASAP] Predictive Model Building for Aggregation Kinetics Based on Molecular Dynamics Simulations of an Antibody Fragment
AI SummaryThis article focuses on building predictive models for aggregation kinetics based on molecular dynamics simulations of an antibody fragment. The research likely delves into understanding the factors affecting the aggregation process of antibodies, which is crucial for the development of stable and effective therapeutic proteins. By studying the molecular dynamics of the antibody fragment,… Continue reading [ASAP] Predictive Model Building for Aggregation Kinetics Based on Molecular Dynamics Simulations of an Antibody Fragment
Structural diversity of the CE-clan proteases in bacteria to disarm host ubiquitin defenses
Editors’ Picks, September 2024: Reducing Pancreatic Cancer Risk, Immunotherapy for Dogs, and More
September is nearing an end, which means it’s time for another edition of Editors’ Picks, our monthly staple featuring articles from AACR’s 10 peer-reviewed journals. This month, the editors have highlighted lifestyle factors that may reduce pancreatic cancer risk, a new humanized mouse model to evaluate treatments for prostate cancer, and innovative therapeutic strategies for… Continue reading Editors’ Picks, September 2024: Reducing Pancreatic Cancer Risk, Immunotherapy for Dogs, and More