Zika virus targets human trophoblast stem cells and prevents syncytialization in placental trophoblast organoids

AI SummaryZika virus infection during pregnancy poses a threat to fetal health, but little is known about its effects on placental trophoblast progenitor cells. This study shows that human trophoblast stem cells (hTSCs) are susceptible to Zika virus infection, and resistance to the virus increases as the cells differentiate. The study also found that the… Continue reading Zika virus targets human trophoblast stem cells and prevents syncytialization in placental trophoblast organoids

Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru

Abstract Highly pathogenic avian influenza (HPAI) A/H5N1 viruses (lineage 2.3.4.4b) are rapidly invading the Americas, threatening wildlife, poultry, and potentially evolving into the next global pandemic. In November 2022 HPAI arrived in Peru, triggering massive pelican and sea lion die-offs. We report genomic characterization of HPAI/H5N1 in five species of marine mammals and seabirds (dolphins,… Continue reading Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru

Antibody production and characterization of the nucleoprotein of sever fever with thrombocytopenia syndrome virus (SFTSV) for effective diagnosis of SFTSV

Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by the Dabie bandavirus, [or SFTS virus (SFTSV)] that has become increasingly widespread since it was first reported in 2009. The… Continue reading on BioMed Central