Virucidal activity of three standard chemical disinfectants against Ebola virus suspended in tripartite soil and whole blood

AI SummaryThe text discusses the importance of disinfecting viruses, particularly the Ebola virus, and the need for efficient and available methods of disinfection. The study developed a standardized protocol to test different chemical disinfectants against Ebola virus variants. The results showed that recommended concentrations of ethanol, sodium hypochlorite, and peracetic acid effectively inactivate the Ebola… Continue reading Virucidal activity of three standard chemical disinfectants against Ebola virus suspended in tripartite soil and whole blood

Nipah virus outbreak: what scientists know so far

AI SummaryThe Nipah virus, a bat-borne virus, has infected six people in Kerala, India, with two deaths. The virus has caused previous outbreaks in the region, and there are concerns about its potential for increased contagion. Nipah virus has a high fatality rate and can cause various symptoms. There are currently no approved vaccines or… Continue reading Nipah virus outbreak: what scientists know so far

[ASAP] Multivalent Dynamic Colocalization of Avian Influenza Polymerase and Nucleoprotein by Intrinsically Disordered ANP32A Reveals the Molecular Basis of Human Adaptation

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Molecular mechanism of de novo replication by the Ebola virus polymerase

Abstract Non-segmented negative-strand RNA viruses (nsNSVs) including Ebola virus (EBOV), rabies virus, human respiratory syncytial virus and pneumoviruses can cause respiratory infections, hemorrhagic fever and encephalitis in the humans and animals, and are considered as substantial health and economic burden worldwide1. Replication and transcription of the viral genome are executed by the large L polymerase… Continue reading Molecular mechanism of de novo replication by the Ebola virus polymerase

TWiV 1043: Marion Koopmans on COVID-19, Mpox, H5N1, polio and One Health

From the European Society for Clinical Virology meeting in Milan, Vincent speaks with Marion Koopmans about COVID-19, Mpox, H5N1 and polio, and the promise of a One Health approach to prevent outbreaks, epidemics, and pandemics. Host: Vincent Racaniello Guest: Marion Koopmans Click arrow to playDownload TWiV 1043 (45 MB .mp3, 62 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email… Continue reading TWiV 1043: Marion Koopmans on COVID-19, Mpox, H5N1, polio and One Health

TWiV 1042: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses China’s health authorities fighting surge in cases of Mpox unknown origin, analysis of seasonal variation of antibiotic prescribing for respiratory tract diagnoses in primary care practices, prevalence and associated outcomes of co-infection between SARS-CoV-2 and influenza, comparison of bivalent and monovalent mRNA vaccine boosters, optimal duration of… Continue reading TWiV 1042: Clinical update with Dr. Daniel Griffin

Zika virus targets human trophoblast stem cells and prevents syncytialization in placental trophoblast organoids

AI SummaryZika virus infection during pregnancy poses a threat to fetal health, but little is known about its effects on placental trophoblast progenitor cells. This study shows that human trophoblast stem cells (hTSCs) are susceptible to Zika virus infection, and resistance to the virus increases as the cells differentiate. The study also found that the… Continue reading Zika virus targets human trophoblast stem cells and prevents syncytialization in placental trophoblast organoids

Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru

Abstract Highly pathogenic avian influenza (HPAI) A/H5N1 viruses (lineage 2.3.4.4b) are rapidly invading the Americas, threatening wildlife, poultry, and potentially evolving into the next global pandemic. In November 2022 HPAI arrived in Peru, triggering massive pelican and sea lion die-offs. We report genomic characterization of HPAI/H5N1 in five species of marine mammals and seabirds (dolphins,… Continue reading Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru

Antibody production and characterization of the nucleoprotein of sever fever with thrombocytopenia syndrome virus (SFTSV) for effective diagnosis of SFTSV

Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by the Dabie bandavirus, [or SFTS virus (SFTSV)] that has become increasingly widespread since it was first reported in 2009. The… Continue reading on BioMed Central