Insulin-mediated endothelin signaling is antiviral during West Nile virus infection

Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim H-S, Miller A, Housden A, Foos M, Randkelv S, Kelley C, Namgyal P, Villalta C, Liu L-P, Jiang X, Huan-Huan Q, Wang X, Fujiyama A, Toyoda A, Ayers K, Blum A, Czech B, Neumuller R, Yan… Continue reading Insulin-mediated endothelin signaling is antiviral during West Nile virus infection

[Editorial] Can we control dengue?

AI SummaryClimate change is leading to an increase in vector-borne diseases, resulting in large dengue outbreaks in Latin America, southeast Asia, and specifically in Bangladesh and Cox’s Bazar. Summary unavailable.Climate change is affecting temperatures and amount of rainfall in many countries, thus favouring the spread of vector-borne diseases. This year, large dengue outbreaks are occurring… Continue reading [Editorial] Can we control dengue?

Blockade of interferon signaling decreases gut barrier integrity and promotes severe West Nile virus disease

AI SummaryThe text discusses the determinants of severe disease caused by West Nile virus (WNV) and the role of gastrointestinal (GI) tract cells in disease severity. When certain immune responses are absent, GI tract cells become infected, leading to increased permeability of the GI tract and blood-brain barrier (BBB), accumulation of gut-derived molecules in the… Continue reading Blockade of interferon signaling decreases gut barrier integrity and promotes severe West Nile virus disease

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

AI SummaryResearchers at the Johns Hopkins Malaria Research Institute have discovered that a protein in Aedes aegypti mosquitoes helps them stay healthy and active when infected with disease-causing viruses. This finding could lead to new methods for reducing the transmission of diseases like dengue, yellow fever, and Zika. The study suggests that targeting this protein… Continue reading Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Discovery in mosquitoes could lead to new strategy against dengue fever and other mosquito-borne vectors

AI SummaryResearchers have discovered new information about Aedes aegypti mosquitoes, which could potentially improve methods for reducing the transmission of harmful viruses like dengue, yellow fever, and Zika.Researchers have made an important finding about Aedes aegypti mosquitoes — one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow… Continue reading Discovery in mosquitoes could lead to new strategy against dengue fever and other mosquito-borne vectors

Author Correction: Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection

AI SummaryThis is a correction to an article published in Nature Communications. It states that two authors were not listed as corresponding authors in the original version, and their email addresses were also missing. The corrections have been made in both the PDF and HTML versions of the article. The text also includes information about… Continue reading Author Correction: Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection

Zika virus infection leads to hormone deficiencies of the hypothalamic-pituitary-gonadal axis and diminished fertility in mice

AI SummaryZika virus (ZIKV) is primarily transmitted by mosquitoes, but can also be sexually transmitted and transmitted vertically from mother to child. It first emerged as a public health concern in 2015 and affected millions of people, causing microcephaly and other complications. ZIKV infection during pregnancy can lead to congenital malformations, but even those without… Continue reading Zika virus infection leads to hormone deficiencies of the hypothalamic-pituitary-gonadal axis and diminished fertility in mice