Tag: Emerging Viruses

Immune response, not acute viral infections, responsible for neurological damage, study finds

AI SummarySummary: A new study challenges the belief that acute viral infections directly cause neurological damage, suggesting that it is the immune system’s response that is responsible. This study challenges the conventional understanding that acute viral infections directly cause neurological damage, such as in cases of Zika or COVID-19. Instead, researchers have found that it… Continue reading Immune response, not acute viral infections, responsible for neurological damage, study finds

TWiV 1085: When macrophages go to alimentary school

TWiV reviews measles outbreaks in England and Europe, 2 fatal Nipah virus cases in Bangladesh, yellow fever outbreak in Sudan, and discuss how the type of immunodeficiency influences the outcome of SARS-CoV-2 infection, and programming of alveolar macrophages by intestinal bacteria that influences severity of respiratory viral infection. Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit… Continue reading TWiV 1085: When macrophages go to alimentary school

New project aims to increase the EU’s ability to combat flavivirus threats

AI SummaryFLAVIVACCINE aims to combat epidemic and pandemic viral threats by developing a pan-flavivirus vaccine candidate. The project focuses on initial infection from mosquito saliva, allowing a single vaccine to protect against multiple diseases. The project covers the entire research and development value chain, improving pandemic preparedness. Ethical considerations were discussed during the inaugural meeting.… Continue reading New project aims to increase the EU’s ability to combat flavivirus threats

Selective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats

Abstract The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African countries, remains unidentified, albeit evidence points towards bats. In contrast, the ecology of the related Marburg virus is much better understood; with experimental infections of bats being instrumental for understanding reservoir-pathogen interactions. Experiments have focused on elucidating reservoir competence, infection… Continue reading Selective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats

Development of a quantitative NS1 antigen enzyme-linked immunosorbent assay (ELISA) for Zika virus detection using a novel virus-specific mAb

Abstract Viruses from the Flaviviridae family, such as Dengue virus (DENV), Yellow fever virus (YFV), and Zika virus (ZIKV) are notorious global public health problems. ZIKV emergence in Polynesia and the Americas from 2013 to 2016 raised concerns as new distinguishing features set it apart from previous outbreaks, including its association with neurological complications and… Continue reading Development of a quantitative NS1 antigen enzyme-linked immunosorbent assay (ELISA) for Zika virus detection using a novel virus-specific mAb

[Media Watch] Africa’s lessons of resiliency and preparedness after Ebola

Tolbert Nyenswah’s book Collapse and resiliency: the inside story of Liberia’s unprecedented Ebola response offers a profound and meticulously detailed exploration of Liberia’s reaction to 2014’s devastating Ebola epidemic. Nyenswah provides a first hand and compelling narrative of the challenges confronted by Liberia, Guinea, and Sierra Leone during this crisis, when he served as the… Continue reading [Media Watch] Africa’s lessons of resiliency and preparedness after Ebola