Tag: Emerging Viruses

A flowchart for adequate controls in virus-based monosynaptic tracing experiments identified Cre-independent leakage of the TVA receptor in RΦGT mice

AI SummaryThis study discusses the development of a flowchart to ensure adequate controls in virus-based monosynaptic tracing experiments. Specifically, the researchers identified Cre-independent leakage of the TVA receptor in RΦGT mice. They used a modified rabies virus lacking the rabies glycoprotein to trace neuronal connections and found unexpected leakage of the TVA receptor. This finding… Continue reading A flowchart for adequate controls in virus-based monosynaptic tracing experiments identified Cre-independent leakage of the TVA receptor in RΦGT mice

Bat ‘nightclubs’ may be the key to solving the next pandemic

AI SummarySummary: Researchers are studying how bats can carry deadly viruses without developing symptoms, focusing on their swarming behavior as a potential key to understanding viral tolerance. This research has implications for human health in combating diseases like Ebola and COVID-19.Researchers are studying how bats can carry deadly viruses, but not develop symptoms. They found… Continue reading Bat ‘nightclubs’ may be the key to solving the next pandemic

TWiV 1089: Shoot out at the Circle-T ranch

AI SummaryThis episode of This Week in Virology (TWiV) covers a fatal Alaskapox case, MERS in Kenya, diagnostic tests for Nipah and Lassa diseases, HPV vaccination rates in the US, cases of measles in Arizona and Minnesota, hepatitis C virus-derived RNA circles in infected cells, and prevention of respiratory virus transmission by resident memory CD8+… Continue reading TWiV 1089: Shoot out at the Circle-T ranch

Synthetic modified vaccinia Ankara vaccines confer cross-reactive and protective immunity against mpox virus

AbstractBackground Although the mpox global health emergency caused by mpox virus (MPXV) clade IIb.1 has ended, mpox cases are still reported due to low vaccination coverage and waning immunity. COH04S1 is a clinically evaluated, multiantigen COVID-19 vaccine candidate built on a fully synthetic platform of the highly attenuated modified vaccinia Ankara (MVA) vector, representing the… Continue reading Synthetic modified vaccinia Ankara vaccines confer cross-reactive and protective immunity against mpox virus

Detecting the impacts of humidity, rainfall, temperature, and season on chikungunya, dengue and Zika viruses in Aedes albopictus mosquitoes from selected sites in Cebu city, Philippines

AI SummarySummary: The study focuses on investigating the impacts of humidity, rainfall, temperature, and season on the presence of chikungunya, dengue, and Zika viruses in Aedes albopictus mosquitoes in selected sites in Cebu City, Philippines. The study aims to determine the minimum infection rates of these viruses in the mosquitoes.Aedes albopictus is the secondary vector… Continue reading Detecting the impacts of humidity, rainfall, temperature, and season on chikungunya, dengue and Zika viruses in Aedes albopictus mosquitoes from selected sites in Cebu city, Philippines

Team creates novel rabies viral vectors for neural circuit mapping

AI SummaryThe research team has developed 20 new recombinant rabies viral vectors for mapping neural circuits. These vectors have several benefits over existing tools and can be used to identify microstructural changes in brain neurons related to aging and Alzheimer’s disease. This research has implications for understanding these conditions and may lead to new insights… Continue reading Team creates novel rabies viral vectors for neural circuit mapping

Climate change drove the emergence of West Nile virus in Europe

AI SummaryThis article discusses how climate change has played a significant role in the emergence of West Nile virus in Europe. Researchers have shown that the virus’s spatial expansion in the continent has been influenced by changing climate conditions. The study highlights an increase in the areas where the virus can thrive ecologically, as well… Continue reading Climate change drove the emergence of West Nile virus in Europe

Immune Response May Cause Virus-Induced Neurologic Damage

AI SummarySummary: The content explains that the results from a mouse model may help in developing therapies to prevent neurologic damage caused by viruses like Zika. This information suggests that the immune response of the body against viruses may be responsible for neurologic damage. The study conducted on mice could potentially lead to the development… Continue reading Immune Response May Cause Virus-Induced Neurologic Damage