Tag: Emerging Viruses

[Articles] Viral shedding and viraemia of Andes virus during acute hantavirus infection: a prospective study

AI SummaryThe article discusses the viral shedding and viraemia of Andes virus during acute hantavirus infection, highlighting the systemic and viraemic nature of the infection. The presence of infectious particles in body fluids aids in understanding potential transmission mechanisms, which can inform preventive strategies. Detection of ANDV RNA in fluids upon hospital admission serves as… Continue reading [Articles] Viral shedding and viraemia of Andes virus during acute hantavirus infection: a prospective study

Single-cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells

AI SummaryThis article discusses a study that used single-cell analysis to identify an antiviral network that controls Zika virus infection in human dendritic cells. The researchers discovered several genes and pathways involved in the immune response to Zika virus, shedding light on potential therapeutic targets for antiviral treatments. This research has important implications for understanding… Continue reading Single-cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells

Trade-offs shaping transmission of sylvatic dengue and Zika viruses in monkey hosts

AI SummaryThis study investigates the transmission of sylvatic dengue and Zika viruses in monkey hosts. It examines the trade-offs involved in virus replication, immune response, and transmission to mosquitoes in cynomolgus macaques and squirrel monkeys. The findings suggest that ZIKV has greater potential than DENV-2 to establish a sylvatic transmission cycle, highlighting immunologically-mediated trade-offs between… Continue reading Trade-offs shaping transmission of sylvatic dengue and Zika viruses in monkey hosts

[Articles] Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccine regimen plus Ad26.ZEBOV booster at 1 year versus 2 years in health-care and front-line workers in the Democratic Republic of the Congo: secondary and exploratory outcomes of an open-label, randomised, phase 2 trial

AI SummaryThe article discusses the findings of a phase 2 trial on the Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccine regimen, with a focus on the secondary and exploratory outcomes. The results show that the regimen and booster dose were well tolerated, and both participants who were boosted 1 year and 2 years after the initial… Continue reading [Articles] Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccine regimen plus Ad26.ZEBOV booster at 1 year versus 2 years in health-care and front-line workers in the Democratic Republic of the Congo: secondary and exploratory outcomes of an open-label, randomised, phase 2 trial

Epitope(s) involving amino acids of the fusion loop of Japanese encephalitis virus envelope protein is(are) important to elicit protective immunity

AI SummaryThis article discusses how specific epitopes involving amino acids in the fusion loop of the Japanese encephalitis virus envelope protein play a crucial role in eliciting a protective immune response. This research highlights the importance of targeting these epitopes for the development of effective vaccines against Japanese encephalitis. By understanding the role of these… Continue reading Epitope(s) involving amino acids of the fusion loop of Japanese encephalitis virus envelope protein is(are) important to elicit protective immunity

Attenuation of A(H7N9) influenza virus infection in mice exposed to cigarette smoke

AI Summaryto its known harmful effects on overall health. Further research is needed to understand the underlying mechanisms and potential implications for human health, especially among smokers who may be at increased risk for severe respiratory infections like A(H7N9) influenza virus.Abstract Influenza A(H7N9) virus showed high pathogenicity in humans when it emerged in 2013. Cigarette… Continue reading Attenuation of A(H7N9) influenza virus infection in mice exposed to cigarette smoke

TWiV 1098: Clinical update with Dr. Daniel Griffin

AI SummaryDr. Griffin provides a clinical update on recent measles, mpox, respiratory syncytial virus, influenza, and SARS-CoV-2 outbreaks. He discusses revised treatment guidelines, the myth of viral rebound, steroid use, convalescent plasma benefits, oxygen therapy in severe cases, COVID-19 effects on children’s cardiovascular system, and altered iron metabolism in long COVID. The episode also addresses… Continue reading TWiV 1098: Clinical update with Dr. Daniel Griffin

[Articles] Effect of single-dose, live, attenuated dengue vaccine in children with or without previous dengue on risk of subsequent, virologically confirmed dengue in Cebu, the Philippines: a longitudinal, prospective, population-based cohort study

AI SummaryThe study explores the impact of a single dose of live, attenuated dengue vaccine on the risk of subsequent virologically confirmed dengue in children with or without prior exposure to dengue in the Philippines. Results indicate that the risk varied based on the individual’s baseline dengue serostatus. While the study doesn’t provide definitive guidance… Continue reading [Articles] Effect of single-dose, live, attenuated dengue vaccine in children with or without previous dengue on risk of subsequent, virologically confirmed dengue in Cebu, the Philippines: a longitudinal, prospective, population-based cohort study