Within 4 days of an outbreak of Sudan Ebola virus disease being confirmed in Uganda, the country had launched a trial with an experimental vaccine. Esther Nakkazi reports.
Tag: Emerging Viruses
Publisher Correction: Baloxavir improves disease outcomes in mice after intranasal or ocular infection with Influenza A virus H5N1-contaminated cow’s milk
Correction to: Nature Microbiology https://doi.org/10.1038/s41564-025-01961-5, published online 17 March 2025. In the version of the article initially published, in Fig. 1d and g, four instances of “≥21.0” appeared incorrectly as “e21.0” and have now been amended in the HTML and PDF versions of the article. Author informationAuthors and Affiliations Department of Host–Microbe Interactions, St. Jude… Continue reading Publisher Correction: Baloxavir improves disease outcomes in mice after intranasal or ocular infection with Influenza A virus H5N1-contaminated cow’s milk
Remember ebola?
Six years before the start of the COVID-19 pandemic, an Ebola outbreak in West Africa had people fearing the possibility of a global outbreak. This was the first time many had ever heard of the virus, but since it was first identified in 1976, there have actually been more than 20 serious Ebola incidents. Thankfully,… Continue reading Remember ebola?
Study reveals distinct infection strategies of Zika and dengue viruses
Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host’s dendritic cells. But a new Nature Communications study, led by scientists at La Jolla Institute for Immunology (LJI) and UC San Diego shows that these two viruses have vastly different ways of making us sick. … Continue reading Study reveals distinct infection strategies of Zika and dengue viruses
How Zika virus knocks out our immune defenses
This research comes as many mosquito-borne viruses are spreading rapidly.
Transmission of bovine H5N1 virus in a hamster model
Jamaican fruit bats’ competence for Ebola but not Marburg virus is driven by intrinsic differences
Abstract Ebola virus (EBOV) and Marburg virus (MARV) are zoonotic filoviruses that cause hemorrhagic fever in humans. Correlative data implicate bats as natural EBOV hosts, but neither a full-length genome nor an EBOV isolate has been found in any bats sampled. Here, we model filovirus infection in the Jamaican fruit bat (JFB), Artibeus jamaicensis, by… Continue reading Jamaican fruit bats’ competence for Ebola but not Marburg virus is driven by intrinsic differences
TWiV 1203: What’s old is flu again
TWiV explains why RFK Jr.’s proposal to let H5N1 infections in birds ‘rip’ is a bad idea, phase 1/2 trial of combined influenza/COVID mRNA vaccines, and how your first influenza virus exposure shapes the B cell response to influenza vaccination 50 years later. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Click arrow to playDownload TWiV… Continue reading TWiV 1203: What’s old is flu again
TWiV 1202: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello rue about the unknowns of Sudan disease and new cases of paralytic polio, discuss the growing measles outbreak, exposure of newborns to measles, the FACTS about vaccination, high pathogenic influenza in dairy cows and cats, RFK’s statement “just let the virus rip through the hens”… Continue reading TWiV 1202: Clinical update with Dr. Daniel Griffin
Current antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Existing antivirals may be less effective against this H5N1 bird flu strain, and prevention measures, such as avoiding raw milk consumption and reducing exposure in dairy workers, may be the most effective way to protect against the virus.