LJI breakthrough offers hope for universal antiviral against filoviruses

AI Summarythe nucleocapsid structure, providing detailed insights into how the virus replicates and evades the host immune response. This breakthrough in imaging technology could lead to the development of a universal antiviral that targets the nucleocapsid structure, offering hope for combatting multiple filoviruses, including Ebola and Marburg. At this moment, the world has few tools… Continue reading LJI breakthrough offers hope for universal antiviral against filoviruses

Paving the way for antivirals against Ebola virus and its deadly relatives

AI SummaryIn this article, scientists have shared detailed images of the Ebola virus nucleocapsid, which could pave the way for the development of antiviral treatments targeting this viral structure. This research has the potential to lead to the creation of antivirals effective against several filoviruses, including the deadly Ebola virus. This breakthrough could significantly advance… Continue reading Paving the way for antivirals against Ebola virus and its deadly relatives

TWiV 1148: Clinical update with Dr. Daniel Griffin

AI SummaryIn this clinical update, Dr. Daniel Griffin discusses various topics related to the COVID-19 pandemic, including new virus strains from farmed fur animals, comparisons between mRNA and pox vectored vaccines, telehealth management of the disease, prophylactic treatments, and the effects of various treatments on outcomes. He also covers statistics on SARS-CoV-2 infections, viral load… Continue reading TWiV 1148: Clinical update with Dr. Daniel Griffin

Epidemiological characteristics and transmission dynamics of dengue fever in China

AI SummaryThis article examines the epidemiological characteristics and transmission dynamics of dengue fever in China based on data from 2013-20. The study found that dengue cases were expanding geographically, with a concentration in southern China. The disease exhibited annual peak activity in September, with variations in amplitude based on latitude. The effective reproduction number (Reff)… Continue reading Epidemiological characteristics and transmission dynamics of dengue fever in China

Targeted immune intervention and stopping ART in model of SIV infection leads to control of viral replication and reservoirs

AI SummaryResearchers have demonstrated successful control of SIV replication and reduction of viral reservoirs by combining a strict infection model with interrupting ART. This immune-based approach builds on understanding the mechanisms of action of PD1 and IL-10 in regulating HIV persistence and immune dysfunction.Researchers have shown unprecedented control of SIV replication and decay of viral… Continue reading Targeted immune intervention and stopping ART in model of SIV infection leads to control of viral replication and reservoirs

Avian flu found in wastewater of 10 Texas cities through virome sequencing

AI SummaryThis article discusses the detection of Avian influenza A(H5N1) virus in the wastewater of 10 Texas cities through virome sequencing. The virus had previously spread to cattle and infected 14 people. This finding highlights the potential for monitoring and tracking the spread of avian flu using wastewater surveillance.Avian influenza A(H5N1) virus, which spread to… Continue reading Avian flu found in wastewater of 10 Texas cities through virome sequencing

Study identifies areas of Europe at risk from dengue fever due to spread of Asian tiger mosquito

AI SummaryThis article discusses a study that identifies areas in Europe at risk for dengue fever due to the spread of the Asian tiger mosquito. The research allows scientists to predict towns on the continent where there is a high risk of the disease. This information is important for public health planning and preparedness efforts… Continue reading Study identifies areas of Europe at risk from dengue fever due to spread of Asian tiger mosquito

Mpox: apply COVID lessons to control outbreak in Africa

AI SummaryThe article discusses how lessons learned from the COVID-19 pandemic can be applied to control the mpox outbreak in Africa. It highlights the need for improved disease surveillance, access to vaccines, and the importance of quickly distributing them to the regions most affected. The lack of resources for tracking the disease, mismatch between suspected… Continue reading Mpox: apply COVID lessons to control outbreak in Africa