Alam Z, Al-Mahdi Z, Zhu Y, McKee Z, Parris DS, Parikh HI, Kellogg GE, Kuchta A, McVoy MA. Anti-cytomegalovirus activity of the anthraquinone atanyl blue PRL. Antiviral Res. 2015;114:86–95. Article CAS PubMed Google Scholar Andersen DO, Weber ND, Wood SG, Hughes BG, Murray BK, North JA. In vitro virucidal activity of selected anthraquinones and anthraquinone… Continue reading Screening and identification of emodin as an EBV DNase inhibitor to prevent its biological functions
Tag: DNA Viruses
DNA element with a murky past is borrowing cell’s repair machinery
Retrotransposons, like their viral cousins, have been observed using the cell’s own machinery to accomplish their objectives. They take over a little-known portion of the cell’s DNA repair process, shape themselves into ring-like structures, and then produce an identical double strand. The discovery challenges 40 years of conventional wisdom and might provide fresh perspectives on… Continue reading DNA element with a murky past is borrowing cell’s repair machinery
TWiV 1007: Fragile DNA, viruses, cancer
TWiV explains genetic changes in nOPV2 strains that paralyzed children, outbreak of raccoon distemper in Toronto, EcoHealth Alliance gets its NIH grant back, and breakage at chromosomal fragile sites caused by the EBNA1 protein of Epstein-Barr virus as a mechanism for carcinogenesis. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Click arrow to playDownload TWiV… Continue reading TWiV 1007: Fragile DNA, viruses, cancer
New mechanism for DNA folding
A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.