Stability and integrity of self-assembled bovine parvovirus virus‑like particles (BPV‑VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment

AI SummaryThis article discusses the stability and integrity of self-assembled bovine parvovirus virus-like particles (BPV-VLPs) of VP2, and a combination of VP1VP2 assisted by baculovirus-insect cell expression. The research focuses on utilizing these VLPs as a potential logistical platform for vaccine deployment. The unique structural properties of BPV are highlighted, emphasizing its potential as a… Continue reading Stability and integrity of self-assembled bovine parvovirus virus‑like particles (BPV‑VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment

The POU-HD TFs impede the replication efficiency of several human papillomavirus genomes

AI SummaryThis article discusses how POU-HD transcription factors can hinder the replication efficiency of various human papillomavirus genomes. HPV is a DNA virus that infects epithelial cells, and replication begins at a specific origin site. The presence of POU-HD TFs can negatively impact this replication process.Human papillomavirus (HPV) is a double-stranded DNA virus that infects… Continue reading The POU-HD TFs impede the replication efficiency of several human papillomavirus genomes

Researchers craft ‘origami DNA’ to control virus assembly

Researchers are modifying the way viruses are put together by using DNA” origami” templates. The international team behind the research came up with a method for precisely and programatically controlling the assembly of virus capsids, the protein shell of viruses, under physiological conditions. The creation of new vaccines and delivery systems would benefit from precise… Continue reading Researchers craft ‘origami DNA’ to control virus assembly