Tag: Coronaviruses
Detection of SARS-CoV-2 in nasopharyngeal swab samples from COVID-19 patients in Riyadh, Saudi Arabia: a PCR-based study
This study involved laboratory experiments using conventional PCR to detect the RNA-dependent RNA polymerase protein (RdRp) and Envelope (E) genes in Forty-Seven nasopharyngeal swab samples from COVID-19 patients… Continue reading on BioMed Central
Designing antivirals for shape-shifting viruses
Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication. However, viruses are dynamic — constantly evolving and changing shape, which can make designing antiviral treatments a challenge.
From rare to more common: The emerging role of omics in improving understanding and treatment of severe inflammatory and hyperinflammatory conditions.
Researchers overlooked airborne diseases for centuries — then COVID-19 changed everything
Air-Borne: The Hidden History of the Life We Breathe Carl Zimmer Dutton (2025) In the first months of the COVID-19 pandemic in 2020, one of the most pressing questions for researchers was how the SARS-CoV-2 virus was transmitted. Some physicians and public-health specialists argued that the virus spread solely in wet droplets from coughing. Others… Continue reading Researchers overlooked airborne diseases for centuries — then COVID-19 changed everything
TWiV 1192: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss confirmation of Robert F Kennedy as HHS sectary, mpox, Ebola, how the American people support vaccine development and administration, the measles outbreak in the US-Texas, Georgia and influenza: the number of human infections, high avian flu in mammals, house cats and dairy cows before… Continue reading TWiV 1192: Clinical update with Dr. Daniel Griffin
Immunocompromised individuals need regular boosters for Covid-19 protection
Vaccinations alone may not be enough to protect people with compromised immune systems from infection, even if the vaccine has generated the production of antibodies, new research from the University of Cambridge has shown. The findings, published today in Science Advances, suggest that such individuals will need regular vaccine boosters to protect them and reduce… Continue reading Immunocompromised individuals need regular boosters for Covid-19 protection
Autoimmunity in Long-COVID
Population shift in antibody immunity following the emergence of a SARS-CoV-2 variant of concern
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) exhibit escape from pre-existing immunity and elicit variant-specific immune responses. In South Africa, the second wave of SARS-CoV-2 infections was driven by the Beta VOC, which coincided with the country-wide National COVID-19 Antibody Survey (NCAS). The NCAS was conducted between November 2020 and… Continue reading Population shift in antibody immunity following the emergence of a SARS-CoV-2 variant of concern
Diverse effects of coronavirus-defective viral genomes on the synthesis of IFNβ and ISG15 mRNAs and coronavirus replication
The mechanism by which coronavirus-defective viral genomes (DVGs) affect coronavirus and host cells during infection remains unclear. A variety of DVGs with different RNA structures can be synthesized from cor… Continue reading on BioMed Central