Finding some stability in adaptable brains

AI SummaryThe content discusses the balance in the brain between stability and flexibility, focusing on individual neurons and synapses in the sensory cortex. Pyramidal neurons have both stable and flexible synapses, with some synapses losing their flexibility by adulthood. The study reveals that stable synapses in a specific region of these neurons have unique properties… Continue reading Finding some stability in adaptable brains

Dorsal root ganglion inflammation by oxaliplatin toxicity: DPEP1 as possible target for peripheral neuropathy prevention

Peripheral neuropathy (PN) constitutes a dose-limiting side effect of oxaliplatin chemotherapy that often compromises the efficacy of antineoplastic treatments. Sensory neurons damage in dorsal root ganglia (D…

Polina Anikeeva named 2024 Blavatnik Award Finalist

AI SummaryThe text discusses Polina Anikeeva being named a 2024 Blavatnik Award finalist for her work in materials science, electronics, and neurobiology to study brain-body communication. She is a professor at MIT focusing on developing technologies for healthy minds and bodies. The Blavatnik Awards recognize young scientists, with Anikeeva being one of the finalists receiving… Continue reading Polina Anikeeva named 2024 Blavatnik Award Finalist

[ASAP] Saroglitazar Enhances Memory Functions and Adult Neurogenesis via Up-Regulation of Wnt/β Catenin Signaling in the Rat Model of Dementia

AI SummaryThis study investigates the effects of the drug saroglitazar on memory functions and adult neurogenesis in a rat model of dementia. The findings suggest that saroglitazar enhances these functions through the up-regulation of Wnt/β-catenin signaling. This research could have implications for the development of new treatments for dementia and cognitive decline.

Trained innate immunity: concept, nomenclature and future perspectives

AI SummaryThis article discusses the concept of trained innate immunity, which refers to the enhanced responsiveness of innate immune cells following exposure to certain stimuli. The nomenclature of this phenomenon is explored, as well as its potential future perspectives in the field of immunology. The article likely delves into the mechanisms behind trained innate immunity,… Continue reading Trained innate immunity: concept, nomenclature and future perspectives

Wearable brain imaging device shines a light on how babies respond in real-world situations

AI SummaryThis article discusses a wearable brain imaging device that utilizes light waves to measure brain activity in babies. It provides a comprehensive understanding of functions such as hearing, vision, and cognitive processing in real-world situations. The device allows for monitoring brain activity without the need for traditional brain scanners, offering new insights into how… Continue reading Wearable brain imaging device shines a light on how babies respond in real-world situations

Musicianship and Prominence of Interhemispheric Connectivity Determine Two Different Pathways to Atypical Language Dominance

AI SummaryThis study explores how musicianship and the prominence of interhemispheric connectivity influence two different pathways to atypical language dominance. It shows that left-handers with atypical language lateralization have enhanced interhemispheric connectivity and rightward participation of language areas. Nonmusicians with atypical lateralization show underdevelopment in the anterior arcuate fasciculus, while musicians show interhemispheric overdevelopment in… Continue reading Musicianship and Prominence of Interhemispheric Connectivity Determine Two Different Pathways to Atypical Language Dominance

ELP1, the Gene Mutated in Familial Dysautonomia, Is Required for Normal Enteric Nervous System Development and Maintenance and for Gut Epithelium Homeostasis

AI SummaryThis article discusses the role of the ELP1 gene in familial dysautonomia (FD) and its impact on the enteric nervous system (ENS) and gut epithelium. It states that ELP1 is essential for the normal development and maintenance of the ENS and for gut epithelium homeostasis. The study found that FD patients and mouse models… Continue reading ELP1, the Gene Mutated in Familial Dysautonomia, Is Required for Normal Enteric Nervous System Development and Maintenance and for Gut Epithelium Homeostasis