Tag: Clinical and Applied Neuroscience

Unique Study Sheds New Light on TBI, Cognitive Decline Link

AI SummaryA study shows that early adulthood traumatic brain injury is linked to cognitive decline later in life, based on research involving World War II twins.Traumatic brain injury that occurs in early adulthood is associated with cognitive decline in later life, results from a study of identical twins who served in World War II show.… Continue reading Unique Study Sheds New Light on TBI, Cognitive Decline Link

[In Context] Simon Lammy

AI SummarySimon Lammy is a senior neurosurgeon and researcher in Glasgow, UK, with a focus on neuro-oncology. He is also involved in teaching and leadership roles in his field.Simon Lammy is a senior neurosurgical specialist registrar at the Institute of Neurological Sciences and a neuro-oncology research fellow at the School of Cancer Sciences in Glasgow,… Continue reading [In Context] Simon Lammy

[In Context] Beyond the modular brain

AI SummaryNeuroscience used to focus on identifying and understanding specific regions of the brain, but this approach oversimplified their functions. In “The Entangled Brain,” Luiz Pessoa argues that it is time for a new perspective that recognizes the interconnectedness of perception, cognition, and emotion in the brain.For much of its history, neuroscience focused on identifying… Continue reading [In Context] Beyond the modular brain

[Comment] Cardiovascular disease after traumatic brain injury: the heart of the matter

AI SummaryThe Lancet Commission on dementia found that traumatic brain injury (TBI) is associated with an increased risk of dementia. Other modifiable risk factors for dementia, such as cardiovascular disease, are also linked to TBI and repetitive head impacts.The 2020 report of the Lancet Commission on dementia prevention, intervention, and care1 summarised the evidence for… Continue reading [Comment] Cardiovascular disease after traumatic brain injury: the heart of the matter

[Personal View] Long-term risk of cardiovascular disease after traumatic brain injury: screening and prevention

AI SummaryTraumatic brain injury (TBI) is common in contact sports, military personnel, and the general population. Besides neurological and psychiatric issues, studies suggest an overlooked link between TBI and chronic cardiovascular diseases. Individuals without previous health conditions who experience TBI have a higher risk of developing cardiovascular diseases.Traumatic brain injury (TBI) is highly prevalent among… Continue reading [Personal View] Long-term risk of cardiovascular disease after traumatic brain injury: screening and prevention

Adding Meaning to Memories: How Parietal Cortex Combines Semantic Content with Episodic Experience

AI SummaryNeuroimaging studies show that parietal cortex in the brain combines information about episodic memory and semantic content. The angular gyrus in the parietal cortex encodes both memory and content information additively, while in the occipitotemporal cortex, memory effects depend on and interact with content representations. These findings shed light on how the brain integrates… Continue reading Adding Meaning to Memories: How Parietal Cortex Combines Semantic Content with Episodic Experience

Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease

AI SummaryThe study explores the relationship between novelty-related brain activity in the locus coeruleus (LC) and the accumulation of tau protein in the cortex, as well as its impact on cognitive decline. The researchers found that lower LC activity during novelty tasks was associated with higher tau deposition in the temporal cortex and greater memory… Continue reading Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease

DATScan in Mild Cognitive Impairment: Some Answers but More Questions

AI SummaryThe text discusses the importance of assessing the in vivo status of the midbrain dopaminergic system in neurodegenerative diseases. It highlights the use of a radiopharmaceutical called FP-CIT, or DATScan, to visualize striatal dopamine transporters. The scan is approved for differentiating essential tremor from neurodegenerative parkinsonian syndromes and for suspected dementia with Lewy bodies.… Continue reading DATScan in Mild Cognitive Impairment: Some Answers but More Questions

In major breakthrough, researchers close in on potential preeclampsia cure

AI SummaryResearchers have identified a toxic protein, cis P-tau, as the primary cause of preeclampsia and are testing an antibody that targets this protein in animal models and human cells. The antibody shows promise in treating preeclampsia as well as traumatic brain injury and Alzheimer’s Disease.Researchers have achieved a significant breakthrough in identifying the primary… Continue reading In major breakthrough, researchers close in on potential preeclampsia cure