Tag: Clinical and Applied Neuroscience

Nasal Spray Shows Promise for Traumatic Brain Injury

A nasal spray developed to combat neuroinflammation has shown promise in treating traumatic brain injury (TBI) in mouse models. The findings were published in Nature Neuroscience and may pave the way for novel treatment options for TBI and other forms of acute brain injury. Neuroinflammation is one of the key mechanisms at work in both… Continue reading Nasal Spray Shows Promise for Traumatic Brain Injury

Nasal Spray Shows Promise for Traumatic Brain Injury

A nasal spray developed to combat neuroinflammation has shown promise in treating traumatic brain injury (TBI) in mouse models. The findings were published in Nature Neuroscience and may pave the way for novel treatment options for TBI and other forms of acute brain injury. Neuroinflammation is one of the key mechanisms at work in both… Continue reading Nasal Spray Shows Promise for Traumatic Brain Injury

Nasal spray shows preclinical promise for treating traumatic brain injury

A new study suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI). By studying the effects of the nasal anti-CD3 in a mouse model of TBI, researchers found the spray could reduce damage to the central nervous system and behavioral deficits, suggesting a potential… Continue reading Nasal spray shows preclinical promise for treating traumatic brain injury

Nasal spray may offer new hope for traumatic brain injury patients

A new study led by researchers at Mass General Brigham suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI). By studying the effects of the nasal anti-CD3 in a mouse model of TBI, researchers found the spray could reduce damage to the central nervous… Continue reading Nasal spray may offer new hope for traumatic brain injury patients

Neuroimaging Model of Visceral Manipulation in an Awake Rat

Reciprocal neuronal connections exist between the internal organs of the body and the nervous system. These projections to and from the viscera play an essential role in maintaining and fine-tuning organ responses in order to sustain homeostasis and allostasis. Functional maps of brain regions participating in this bidirectional communication have been previously studied in awake… Continue reading Neuroimaging Model of Visceral Manipulation in an Awake Rat

[In Context] An ethical framework to assess covert consciousness

The potential for cognitive motor dissociation in patients who are behaviourally unresponsive after a severe brain injury poses profound ethical challenges. An international study revealed that one in four patients who appear unresponsive to verbal commands is capable of doing cognitive tasks detected through functional MRI or EEG (ie, has cognitive motor dissociation). Cognitive motor… Continue reading [In Context] An ethical framework to assess covert consciousness

Motor Functional Hierarchical Organization of Cerebrum and Its Underlying Genetic Architecture in Parkinsons Disease

Hierarchy has been identified as a principle underlying the organization of human brain networks. However, it remains unclear how the network hierarchy is disrupted in Parkinson’s disease (PD) motor symptoms and how it is modulated by the underlying genetic architecture. The aim of this study was to explore alterations in the motor functional hierarchical organization… Continue reading Motor Functional Hierarchical Organization of Cerebrum and Its Underlying Genetic Architecture in Parkinsons Disease