AI SummaryThis study examines the relationship between gray matter volume (GMV) and slow-wave characteristics in patients with traumatic brain injury (TBI) compared to healthy controls. While GMV in specific brain regions was associated with slow-wave frequency and morphology in healthy individuals, this relationship was not observed in TBI patients, despite lower GMV. This challenges the… Continue reading Cerebral Gray Matter May Not Explain Sleep Slow-Wave Characteristics after Severe Brain Injury
Tag: Clinical and Applied Neuroscience
Walking the walk, scientists develop motion-compatible brain scanner
AI SummaryThis article discusses the development of an upright neuroimaging device that allows patients to move around while undergoing a brain scan. This innovative technology was developed by a collaboration of neuroscientists, physicists, and engineers. This motion-compatible brain scanner has the potential to provide more accurate and real-life data about brain activity compared to traditional… Continue reading Walking the walk, scientists develop motion-compatible brain scanner
Thalamocortical mGlu8 Modulates Dorsal Thalamus Excitatory Transmission and Sensorimotor Activity
AI SummaryThis article explores the role of the metabotropic glutamate receptor 8 (mGlu8) in modulating excitatory transmission in the dorsal thalamus and sensorimotor activity. The study demonstrates that perturbing grm8 signaling in the thalamocortical circuit leads to increased excitatory drive onto dorsal thalamus relay cells and impairs sensorimotor gating in mice. Additionally, the research shows… Continue reading Thalamocortical mGlu8 Modulates Dorsal Thalamus Excitatory Transmission and Sensorimotor Activity
Neural Representation of Valenced and Generic Probability and Uncertainty
AI SummaryThe article examines how the brain represents probability and uncertainty of different types of outcomes, including valenced (appetitive or aversive) and neutral outcomes. Using human neuroimaging in a Pavlovian task, the study found that cues predicting valenced outcomes with higher probability elicited faster motor responses and larger pupil sizes, while cues predicting neutral outcomes… Continue reading Neural Representation of Valenced and Generic Probability and Uncertainty
[In Context] Women in Neurosurgery: breaking barriers
AI SummaryThis article discusses the slow progress of gender parity in the field of neurosurgery, with Women in Neurosurgery (WINS) playing a significant role in advocating for and supporting female neurosurgeons. Despite the improvement in female representation in neurosurgery residency programs and practicing neurosurgeons over the years, there is still work to be done to… Continue reading [In Context] Women in Neurosurgery: breaking barriers
[In Context] Nazia Karsan
AI SummaryNazia Karsan is a neurologist and post-doctoral Clinical Research Fellow at King’s College London, UK. She focuses on researching headache, specifically studying the neurobiological mechanisms of migraine. Her work involves using functional neuroimaging to understand migraine and the mechanisms of allodynia.Nazia Karsan is a neurologist and post-doctoral Clinical Research Fellow at King’s College London,… Continue reading [In Context] Nazia Karsan
[Comment] Detection of awareness after brain injury: time for change
AI SummaryThe article discusses the challenges of accurately predicting outcomes after acute brain injury and the need for improved prognostic tools. Withdrawal of life-sustaining therapies based on poor prognoses is a common cause of death, but the timing of this decision varies significantly between centers. The author suggests a need for change in how awareness… Continue reading [Comment] Detection of awareness after brain injury: time for change
[Personal View] Detecting awareness after acute brain injury
AI SummaryThe text discusses how functional neuroimaging advancements have allowed for the detection of preserved cognitive function in patients with severe brain injuries, even during the acute phase when prognosis is uncertain. Techniques like functional MRI and EEG have been utilized to identify covert conscious awareness in behaviorally unresponsive patients, providing new diagnostic and prognostic… Continue reading [Personal View] Detecting awareness after acute brain injury
Erratum: Huang et al., “Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury”
Study reveals how an anesthesia drug induces unconsciousness
AI SummaryResearchers at MIT have discovered that the anesthesia drug propofol induces unconsciousness by disrupting the brain’s balance between stability and excitability, ultimately leading to instability in brain activity. This new finding could help in developing tools for better monitoring patients under general anesthesia. The study also suggests that other anesthetic drugs might lead to… Continue reading Study reveals how an anesthesia drug induces unconsciousness