The potential for cognitive motor dissociation in patients who are behaviourally unresponsive after a severe brain injury poses profound ethical challenges. An international study revealed that one in four patients who appear unresponsive to verbal commands is capable of doing cognitive tasks detected through functional MRI or EEG (ie, has cognitive motor dissociation). Cognitive motor… Continue reading [In Context] An ethical framework to assess covert consciousness
Tag: Clinical and Applied Neuroscience
Motor Functional Hierarchical Organization of Cerebrum and Its Underlying Genetic Architecture in Parkinsons Disease
Hierarchy has been identified as a principle underlying the organization of human brain networks. However, it remains unclear how the network hierarchy is disrupted in Parkinson’s disease (PD) motor symptoms and how it is modulated by the underlying genetic architecture. The aim of this study was to explore alterations in the motor functional hierarchical organization… Continue reading Motor Functional Hierarchical Organization of Cerebrum and Its Underlying Genetic Architecture in Parkinsons Disease
[ASAP] Microglial Autophagic Dysregulation in Traumatic Brain Injury: Molecular Insights and Therapeutic Avenues
Neurological Pupil Index and Intracranial Hypertension in Patients With Acute Brain Injury
This secondary analysis of the ORANGE study evaluates whether an association exists between the Neurological Pupil Index and invasive intracranial pressure.
Defining the Clinical Phenotype of the Activated Phosphoinositide 3-Kinase δ Syndrome (APDS) Cohort at the University of South Florida
Professor Emeritus Gerald Schneider, discoverer of the “two visual systems,” dies at 84
Gerald E. Schneider, a professor emeritus of psychology and member of the MIT community for over 60 years, passed away on Dec. 11, 2024. He was 84. Schneider was an authority on the relationships between brain structure and behavior, concentrating on neuronal development, regeneration or altered growth after brain injury, and the behavioral consequences of… Continue reading Professor Emeritus Gerald Schneider, discoverer of the “two visual systems,” dies at 84
Early Signs of Huntington’s Detectable Long Before Symptoms
Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms of Huntington’s disease present. Medscape Medical News
[In Context] Pengfei Yang
Pengfei Yang is professor of neurosurgery and executive director of the neurovascular centre at Changhai Hospital, Naval Medical University (Shanghai, China). He obtained his medical degree from Zhejiang University (Hangzhou, China) and did his postdoctoral research on interventional neuroradiology at the University of Wisconsin-Madison (Madison, WI, USA). He leads a series of trials focusing on… Continue reading [In Context] Pengfei Yang
[In Context] Standing in Cushing’s shadow
Brain surgery, like rocket science, has become a byword in popular culture for an intellectually challenging and risky pursuit. Its practitioners, at least according to their portrayal in popular culture, are either brilliant but arrogant renaissance men or reckless experimenters. But where do these stereotypes come from and do they reflect the reality of life… Continue reading [In Context] Standing in Cushing’s shadow
[Editorial] Traumatic brain injury in older adults: a neglected challenge
Worldwide, at least 38 million people had a traumatic brain injury in 2021. The greatest burden of injury is faced by older people: disability-adjusted life years (DALYs; a measure of disease burden) are high in older adults (176·5 DALYs per 100 000 at age 60–79 years and 226·3 per 100 000 at age ≥80 years) compared with… Continue reading [Editorial] Traumatic brain injury in older adults: a neglected challenge