Novel strategy can potentially control MAPK4-promoted growth in triple negative breast cancer

In 2022, a team of researchers at Baylor College of Medicine discovered that a little-known enzyme called MAPK4 is involved in the growth of triple negative breast cancer (TNBC) and its resistance to certain therapies. Looking into the details of this novel role of MAPK4, the researchers have now identified a strategy that can potentially… Continue reading Novel strategy can potentially control MAPK4-promoted growth in triple negative breast cancer

Hybrid molecules of protoflavones and indole derivatives with selective cytotoxicity against triple-negative breast cancer cells

RSC Med. Chem., 2023, Accepted ManuscriptDOI: 10.1039/D3MD00251A, Research Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gábor Girst, Elizabeth A Lopes, Lídia M. Gonçalves, Margarida Espadinha, Norbert Kúsz, Hui-Chun Wang, Maria M. M. Santos, Attila HunyadiThe combination of compounds with complementary bioactivities into hybrid molecules is an emerging… Continue reading Hybrid molecules of protoflavones and indole derivatives with selective cytotoxicity against triple-negative breast cancer cells

From the Bench: Creative Approaches in Cancer Research

Improved patient outcomes come from new treatments. New treatments stem from successful clinical trials. Clinical trials build on discoveries made in the lab. And laboratory discoveries? Those rely on a vast array of assays and specialized technologies, combined with the ingenuity of bench scientists who devise, master, and apply these tools in creative ways to… Continue reading From the Bench: Creative Approaches in Cancer Research

Accounting for Medicaid expansion and regional policy and programs to advance equity in cancer prevention in the United States

The study looked at how Medicaid expansion affected cancer diagnosis and treatment in two states, Ohio and Georgia . The researchers found that, after Ohio expanded their Medicaid program, there were more patients with cancer among low-income adults on Medicaid . In Ohio, the largest increase in all three cancer types was observed in the… Continue reading Accounting for Medicaid expansion and regional policy and programs to advance equity in cancer prevention in the United States

Accounting for Medicaid expansion and regional policy and programs to advance equity in cancer prevention in the United States

The study looked at how Medicaid expansion affected cancer diagnosis and treatment in two states, Ohio and Georgia . The researchers found that, after Ohio expanded their Medicaid program, there were more patients with cancer among low-income adults on Medicaid . In Ohio, the largest increase in all three cancer types was observed in the… Continue reading Accounting for Medicaid expansion and regional policy and programs to advance equity in cancer prevention in the United States

Engaging black sexual minority women in breast cancer research: Lessons in community partnerships

There exists no peer-reviewed literature on best practices for the inclusion of BSMW in cancer research . “Our Breast Health: The Access Project” was a national primary data collection study in June 2018 through October 2019 that aimed to identify facilitators and barriers to breast cancer care . Community-based organizations were 26 times more successful… Continue reading Engaging black sexual minority women in breast cancer research: Lessons in community partnerships

Engaging black sexual minority women in breast cancer research: Lessons in community partnerships

There exists no peer-reviewed literature on best practices for the inclusion of BSMW in cancer research . “Our Breast Health: The Access Project” was a national primary data collection study in June 2018 through October 2019 that aimed to identify facilitators and barriers to breast cancer care . Community-based organizations were 26 times more successful… Continue reading Engaging black sexual minority women in breast cancer research: Lessons in community partnerships

Breast cancer risk characteristics of women undergoing whole‐breast ultrasound screening versus mammography alone

There are no consensus guidelines for supplemental breast cancer screening with whole-breast ultrasound . 95.3% of 38,166 screening ultrasounds were among women with heterogeneously or extremely dense breasts . A clinically significant proportion of women undergoing mammography screening alone were at high screening failure risk .

Oncofertility‐related psycho‐educational therapy for young adult patients with breast cancer and their partners: Randomized controlled trial

A couples’ psycho-educational program called Oncofertility! Psycho-Education and Couple Enrichment (O!PEACE) therapy was created and its effect when provided before cancer treatment was examined . Primary end points were cancer-related posttraumatic stress symptoms, symptoms of depression, anxiety, stress-coping strategies, resilience, and marital relationship . A >5-point reduction was present in 59.3% and 30% of women… Continue reading Oncofertility‐related psycho‐educational therapy for young adult patients with breast cancer and their partners: Randomized controlled trial