AI SummaryThe article discusses how some bacteria modulate their cell walls with D-alanine residues as a defense mechanism against bacteriophages that rely on wall teichoic acid (WTA) as a receptor. A chemical inhibitor of WTA D-alanylation was used to increase bacterial susceptibility to phage infection in Bacillus subtilis. The study revealed the breadth of immunity… Continue reading Chemical inhibition of cell surface modification sensitizes bacteria to phage infection
Tag: Bacteriophages
How to introduce a new bacteriophage on the block: a short guide to phage classification
AI SummaryThis article provides a short guide on how to introduce a new bacteriophage into existing phage classification systems. It discusses the importance of accurately classifying bacteriophages and outlines the steps involved in the classification process. The article aims to help researchers effectively categorize and study bacteriophages in order to better understand their impact on… Continue reading How to introduce a new bacteriophage on the block: a short guide to phage classification
[ASAP] Formulation of Dual-Functional Nonionic Cetomacrogol Creams Incorporated with Bacteriophage and Human Platelet Lysate for Effective Targeting of MDR P. aeruginosa and Enhanced Wound Healing
ACS Applied Bio MaterialsDOI: 10.1021/acsabm.4c00747
Genomic transfer via membrane vesicle: a strategy of giant phage phiKZ for early infection
Erratum for Noh et al., “Identification of Anaplasma marginale adhesins for entry into Dermacentor andersoni tick cells using phage display”
Infection and Immunity, Ahead of Print.
Variable fitness effects of bacteriophage resistance mutations in Escherichia coli: implications for phage therapy
AI SummaryThis study examines the fitness effects of bacteriophage resistance mutations in Escherichia coli, exploring how different mutations impact the ability of the bacteria to survive and reproduce. The research highlights the variability in fitness effects among resistance mutations and discusses the implications of these findings for the effectiveness of phage therapy as a treatment… Continue reading Variable fitness effects of bacteriophage resistance mutations in Escherichia coli: implications for phage therapy
Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly
AI SummaryThe article discusses the mechanisms by which bacteria use a ubiquitin-like protein system as an antiphage defense during phage infection. Specifically, the system conjugates the ubiquitin-like protein to the phage central tail fibre, interfering with phage assembly. This study sheds light on a novel defense mechanism in bacteria and provides insights into how bacteria… Continue reading Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly
Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin
AI SummaryThe study explores the use of immunogenic cell death (ICD) marker ERp57 as a target for Chimeric antigen receptor natural killer (CAR-NK) therapy in solid tumors. The research demonstrates that ERp57 translocated to the cell surface after drug treatment can be targeted using CAR-NK cells, leading to robust antitumor activity in various tumor cell… Continue reading Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin
Identification of Babesia microti immunoreactive antigens by phage display cDNA screen
Infection and Immunity, Ahead of Print.