AI SummaryThis article discusses a recent study that provides new insight into the causes of autoimmune diseases. Researchers have discovered that the body’s own proteins with unusual structure can trigger immune cells to attack its own tissues, leading to autoimmunity. The study found that when the MHC-II is missing a crucial piece called the invariant… Continue reading New insight into the causes of autoimmune diseases
Tag: Autoimmunity and Autoimmune Diseases
Does Multiple Sclerosis Protect Against Alzheimer’s?
Patients with MS showed half the rate of amyloid pathology compared with people without MS, suggesting a possible protective effect against Alzheimer’s disease. Medscape Medical News
Autoimmune bullous diseases induced by cyclin-dependent kinase 4/6 inhibitors—first cohort from the EADV Task Force ‘Dermatology for Cancer Patients’
AI SummaryThis article discusses the occurrence of autoimmune bullous diseases in a cohort of European patients due to the use of cyclin-dependent kinase (CDK) 4/6 inhibitors such as palbociclib and ribociclib. While dermatologic adverse events of CDK 4/6 inhibitors are relatively common, bullous lesions are rare. The study sheds light on this specific side effect… Continue reading Autoimmune bullous diseases induced by cyclin-dependent kinase 4/6 inhibitors—first cohort from the EADV Task Force ‘Dermatology for Cancer Patients’
Immune Booster #9: Autoimmune diseases with Mark Shlomchik
AI SummaryIn this podcast episode, hosts Cindy and Steph interview Mark Shlomchik at the American Association of Immunologists 2024 conference in Chicago. Shlomchik discusses his research on systemic autoimmune diseases, long-lived B cell immunity, and immunopathogenesis. The conversation provides insights into the work and career of Shlomchik in the field of immunology. From the American… Continue reading Immune Booster #9: Autoimmune diseases with Mark Shlomchik
Exclusive-Teva Faces EU Fine for Disparaging Rival Multiple Sclerosis Medicine, Sources Say
AI SummaryThe world’s largest generic drugmaker, Teva, is facing an EU antitrust fine for disparaging a rival multiple sclerosis medicine, according to sources. This action highlights the importance of fair competition and the consequences of negative practices in the pharmaceutical industry.Teva, the world’s largest generic drugmaker, will be hit with an EU antitrust fine in… Continue reading Exclusive-Teva Faces EU Fine for Disparaging Rival Multiple Sclerosis Medicine, Sources Say
cGAS activation in classical dendritic cells causes autoimmunity in TREX1-deficient mice
Author Correction: Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus
AI SummaryThis article provides a correction to a previous publication related to genetic variants in UNC93B1 predisposing to childhood-onset systemic lupus erythematosus. Two missing references have been added to the article, providing additional information on the topic. The authors listed are from various institutions in China, Yemen, Russia, and Australia. Correction to: Nature Immunology https://doi.org/10.1038/s41590-024-01846-5,… Continue reading Author Correction: Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus
When a double negative is not a positive: Autoantibodies against IL-10 in patients with inflammatory bowel disease
Science Immunology, Volume 9, Issue 99, September 2024.
Cancer drug offers life-changing results for severe lupus patient
AI SummaryThe cancer drug teclistamab has shown remarkable results in treating a severe case of systemic lupus erythematosus (SLE) in a 23-year-old patient, who went from being wheelchair-bound to completely symptom-free after six months of treatment. This case has been published in the New England Journal of Medicine and marks a promising starting point for… Continue reading Cancer drug offers life-changing results for severe lupus patient
Novel study reveals how aging immune system fuels cancer growth, potentially opening new avenues for prevention
AI SummaryIn a novel study, researchers have discovered that an aging immune system accelerates tumor growth, shedding light on why aging is a significant risk factor for cancer. The findings suggest that the drug anakinra, commonly used for inflammatory conditions, could potentially be repurposed to prevent tumor growth by blocking harmful signals between early cancer… Continue reading Novel study reveals how aging immune system fuels cancer growth, potentially opening new avenues for prevention